Revenue Recognition - Schedule of Product Sales Allowances and Accruals (Details) - USD ($)	3 Months Ended		9 Months Ended		12 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021	Dec. 31, 2021
Accounts Receivable, Allowance for Credit Loss [Roll Forward]
Provision related to current period sales	$ 57,900	$ 29,300	$ 241,500	$ 636,100
Total revenues	179,744,000	385,813,000	818,856,000	1,373,387,000
Rayaldee
Accounts Receivable, Allowance for Credit Loss [Roll Forward]
Beginning balance	9,776,000	12,611,000	10,152,000	11,737,000	$ 11,737,000
Provision related to current period sales	7,618,000	6,880,000	25,131,000	27,809,000
Credits or payments made	(6,553,000)	(10,754,000)	(24,442,000)	(30,809,000)
Ending balance	10,841,000	8,737,000	10,841,000	8,737,000	10,152,000
Total revenues	$ 14,497,000	$ 15,332,000	$ 43,358,000	$ 47,099,000
Provision for Rayaldee sales allowances and accruals as a percentage of gross Rayaldee sales	53.00%	45.00%	58.00%	59.00%
Chargebacks, discounts, rebates and fees | Rayaldee
Accounts Receivable, Allowance for Credit Loss [Roll Forward]
Beginning balance	$ 1,669,000	$ 1,701,000	$ 2,014,000	$ 2,332,000	2,332,000
Provision related to current period sales	3,191,000	3,315,000	9,816,000	10,854,000
Credits or payments made	(2,892,000)	(3,616,000)	(9,862,000)	(11,786,000)
Ending balance	1,968,000	1,400,000	1,968,000	1,400,000	2,014,000
Governmental | Rayaldee
Accounts Receivable, Allowance for Credit Loss [Roll Forward]
Beginning balance	6,489,000	7,586,000	5,499,000	5,812,000	5,812,000
Provision related to current period sales	4,158,000	3,258,000	14,469,000	16,013,000
Credits or payments made	(3,261,000)	(6,733,000)	(12,582,000)	(17,714,000)
Ending balance	7,386,000	4,111,000	7,386,000	4,111,000	5,499,000
Returns | Rayaldee
Accounts Receivable, Allowance for Credit Loss [Roll Forward]
Beginning balance	1,618,000	3,324,000	2,639,000	3,593,000	3,593,000
Provision related to current period sales	269,000	307,000	846,000	942,000
Credits or payments made	(400,000)	(405,000)	(1,998,000)	(1,309,000)
Ending balance	$ 1,487,000	$ 3,226,000	$ 1,487,000	$ 3,226,000	$ 2,639,000