Revenue Recognition - Schedule of Product Sales Allowances and Accruals (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended		12 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Accounts Receivable, Allowance for Credit Loss [Roll Forward]
Provision related to current period sales	$ 100	$ 300	$ 200	$ 600
Total revenues	309,893	442,408	639,111	987,573
Rayaldee
Accounts Receivable, Allowance for Credit Loss [Roll Forward]
Beginning balance	9,203	11,389	10,152	11,737	$ 11,737
Provision related to current period sales	9,161	11,107	17,514	20,929
Credits or payments made	(8,588)	(9,885)	(17,890)	(20,055)
Ending balance	9,776	12,611	9,776	12,611	10,152
Total revenues	$ 15,382	$ 16,122	$ 28,861	$ 31,767
Provision for Rayaldee sales allowances and accruals as a percentage of gross Rayaldee sales	60.00%	69.00%	61.00%	66.00%
Chargebacks, discounts, rebates and fees | Rayaldee
Accounts Receivable, Allowance for Credit Loss [Roll Forward]
Beginning balance	$ 1,588	$ 1,693	$ 2,014	$ 2,332	2,332
Provision related to current period sales	3,411	3,724	6,626	7,539
Credits or payments made	(3,330)	(3,716)	(6,971)	(8,170)
Ending balance	1,669	1,701	1,669	1,701	2,014
Governmental | Rayaldee
Accounts Receivable, Allowance for Credit Loss [Roll Forward]
Beginning balance	5,282	6,209	5,499	5,812	5,812
Provision related to current period sales	5,442	7,061	10,311	12,755
Credits or payments made	(4,235)	(5,684)	(9,321)	(10,981)
Ending balance	6,489	7,586	6,489	7,586	5,499
Returns | Rayaldee
Accounts Receivable, Allowance for Credit Loss [Roll Forward]
Beginning balance	2,333	3,487	2,639	3,593	3,593
Provision related to current period sales	308	322	577	635
Credits or payments made	(1,023)	(485)	(1,598)	(904)
Ending balance	$ 1,618	$ 3,324	$ 1,618	$ 3,324	$ 2,639