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Acquisitions and Investments - Narrative (Details) - USD ($)
$ / shares in Units, $ in Thousands
2 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
May 09, 2022
Apr. 29, 2022
Sep. 14, 2021
Jun. 30, 2022
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Dec. 31, 2021
Schedule of Equity Method Investments [Line Items]                  
Value of consideration shares             $ 172,000 $ 0  
Total assets of equity method investees       $ 2,369,602 $ 2,369,602   2,369,602   $ 2,399,715
Total liabilities of equity method investees       650,803 650,803   650,803   714,589
Market value       1,900 1,900   1,900   4,500
Upfront payment received         309,893 $ 442,408 639,111 987,573  
Transfer of intellectual property and other                  
Schedule of Equity Method Investments [Line Items]                  
Upfront payment received         87,197 $ 9,548 93,159 $ 13,816  
LeaderMed | LeaderMed Joint Venture | Corporate Joint Venture                  
Schedule of Equity Method Investments [Line Items]                  
Joint venture (in shares)     4,703            
Ownership interest in joint venture (as a percent)     47.00%            
LeaderMed | LeaderMed Joint Venture | Corporate Joint Venture | Transfer of intellectual property and other                  
Schedule of Equity Method Investments [Line Items]                  
Upfront payment received     $ 1,000           1,000
Equity Method Investment, Nonconsolidated Investee or Group of Investees                  
Schedule of Equity Method Investments [Line Items]                  
Total assets of equity method investees       212,400 212,400   212,400   223,600
Total liabilities of equity method investees       $ 41,700 $ 41,700   41,700   37,900
Net losses of equity method investees             $ 48,600   $ 69,400
Pharmsynthez                  
Schedule of Equity Method Investments [Line Items]                  
Equity method investments (as a percent)       9.00% 9.00%   9.00%    
Cocrystal                  
Schedule of Equity Method Investments [Line Items]                  
Equity method investments (as a percent)       3.00% 3.00%   3.00%    
Number of shares into which warrants may be converted (in shares)       33,000 33,000   33,000    
Non-Invasive Monitoring Systems, Inc.                  
Schedule of Equity Method Investments [Line Items]                  
Equity method investments (as a percent)       1.00% 1.00%   1.00%    
Neovasc                  
Schedule of Equity Method Investments [Line Items]                  
Equity method investments (as a percent)       1.00% 1.00%   1.00%    
BioCardia, Inc.                  
Schedule of Equity Method Investments [Line Items]                  
Equity method investments (as a percent)       1.00% 1.00%   1.00%    
Equity security investments (as a percent)       1.00% 1.00%   1.00%    
Number of shares into which warrants may be converted (in shares)       47,000 47,000   47,000   47,000
Xenetic Biosciences, Inc.                  
Schedule of Equity Method Investments [Line Items]                  
Equity method investments (as a percent)       3.00% 3.00%   3.00%    
LeaderMed                  
Schedule of Equity Method Investments [Line Items]                  
Stock ownership (as a percent)             47.00%    
Sema4                  
Schedule of Equity Method Investments [Line Items]                  
Net losses for fair value changes in investment   $ 71,200              
Phio Pharmaceuticals                  
Schedule of Equity Method Investments [Line Items]                  
Equity security investments (as a percent)       0.01% 0.01%   0.01%    
VBI Vaccines Inc                  
Schedule of Equity Method Investments [Line Items]                  
Equity security investments (as a percent)       1.00% 1.00%   1.00%    
ChromaDex                  
Schedule of Equity Method Investments [Line Items]                  
Equity security investments (as a percent)       0.10% 0.10%   0.10%    
Eloxx Pharmaceuticals                  
Schedule of Equity Method Investments [Line Items]                  
Equity security investments (as a percent)       1.00% 1.00%   1.00%    
CAMP4                  
Schedule of Equity Method Investments [Line Items]                  
Equity security investments (as a percent)       2.00% 2.00%   2.00%    
HealthSnap                  
Schedule of Equity Method Investments [Line Items]                  
Equity security investments (as a percent)       7.00% 7.00%   7.00%    
InCellDx, Inc                  
Schedule of Equity Method Investments [Line Items]                  
Equity method investments (as a percent)       29.00% 29.00%   29.00%    
Number of shares into which warrants may be converted (in shares)       700,000 700,000   700,000    
Zebra                  
Schedule of Equity Method Investments [Line Items]                  
Stock ownership (as a percent)             29.00%    
Zebra | Variable Interest Entity, Not Primary Beneficiary                  
Schedule of Equity Method Investments [Line Items]                  
Equity method investments (as a percent)       29.00% 29.00%   29.00%    
Series A Preferred Stock | Zebra | Variable Interest Entity, Not Primary Beneficiary                  
Schedule of Equity Method Investments [Line Items]                  
Investment owned (in shares)       1,260,000 1,260,000   1,260,000    
Restricted Stock | Zebra | Variable Interest Entity, Not Primary Beneficiary                  
Schedule of Equity Method Investments [Line Items]                  
Shares received as a gift (in shares)             900,000    
Common Stock                  
Schedule of Equity Method Investments [Line Items]                  
Stock price (in dollars per share) $ 2.44                
Sema4 | Sema4                  
Schedule of Equity Method Investments [Line Items]                  
Equity method investments (as a percent)       21.20% 21.20%   21.20%    
Sema4 | Common Class A                  
Schedule of Equity Method Investments [Line Items]                  
Investment owned (in shares)       80,000,000 80,000,000   80,000,000    
ModeX Therapeutics Inc                  
Schedule of Equity Method Investments [Line Items]                  
Total aggregate consideration $ 300,000                
Total purchase price 221,662                
Vested equity awards 2,300                
Revenue       $ 0          
Net income (loss)       $ 1,100          
ModeX Therapeutics Inc | Common Stock                  
Schedule of Equity Method Investments [Line Items]                  
Value of consideration shares $ 219,400                
Stock price (in dollars per share) $ 2.44                
Detect Genomix | Sema4                  
Schedule of Equity Method Investments [Line Items]                  
Total aggregate consideration   447,000              
Payments to acquire business   $ 150,000              
Outstanding shares held (as a percent)   5.00%