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Strategic Alliances (Details) - USD ($)
1 Months Ended 3 Months Ended 87 Months Ended
Sep. 14, 2021
Jul. 06, 2021
Jun. 18, 2021
May 05, 2020
Oct. 21, 2019
Apr. 30, 2022
May 31, 2016
Jan. 31, 2015
Mar. 31, 2022
Mar. 31, 2021
Mar. 31, 2022
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Total revenues                 $ 329,219,000 $ 545,165,000  
Milestone revenue recognized                 4,000    
LeaderMed | LeaderMed Joint Venture | Corporate Joint Venture                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Ownership interest in joint venture (as a percent) 47.00%                    
Initial investment in joint venture $ 11,000,000                    
Ownership percentage by related parties (as a percent) 53.00%                    
CAMP4                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Upfront payment (in shares)   3,373,008                  
Outstanding shares (as a percent)   9.00%                  
Period following first commercial sale in a country   10 years                  
Nicoya                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Upfront payment from development and license agreement     $ 5,000,000                
Period after first commercial sale     10 years                
Pfizer | Products                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Maximum milestone payments               $ 275,000,000      
Annual height velocity at point in time         12 months            
Initial upfront payment               295,000,000      
Additional milestone payment               275,000,000      
Milestone revenue recognized                     $ 0
Pfizer | Products | Subsequent Event                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Milestone payments           $ 85,000,000          
Minimum | Pfizer | Products                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Milestone payments               20,000,000      
Maximum | Pfizer | Products                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Milestone payments               $ 90,000,000      
Phase Three Initiation | Nicoya                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Upfront payment from development and license agreement     $ 5,000,000                
Regulatory and Development | Nicoya                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Milestone payment from development and license agreement     $ 115,000,000                
Transfer of intellectual property and other                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Total revenues                 5,962,000 4,269,000  
Transfer of intellectual property and other | Products                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Total revenues       $ 3,000,000              
Transfer of intellectual property and other | LeaderMed | LeaderMed Joint Venture | Corporate Joint Venture                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Total revenues $ 1,000,000               1,000,000    
Transfer of intellectual property and other | CAMP4                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Total revenues   $ 1,500,000                  
Transfer of intellectual property and other | VFMCRP | Products                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Total revenues                 3,000,000    
Transfer of intellectual property and other | Pfizer | Products                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Total revenues                 2,200,000 2,800,000  
Dravet Syndrome Products | CAMP4                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Development milestone payments   3,500,000                  
Sales milestone payments   $ 90,000,000                  
Development milestone payments (in shares)   5,782,299                  
Non-Dravet Syndrome Products | CAMP4                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Development milestone payments   $ 4,000,000                  
Sales milestone payments   $ 90,000,000                  
Development milestone payments (in shares)   1,082,248                  
Products                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Total revenues                 $ 36,658,000 $ 33,945,000  
Regulatory Milestones | EirGen Pharma Limited                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Maximum milestone payments       17,000,000              
Sales Milestones | EirGen Pharma Limited                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Maximum milestone payments       $ 207,000,000              
Exclusive Option | VFMCRP                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Maximum milestone payments             $ 555,000,000