Revenue Recognition - Schedule of Product Sales Allowances and Accruals (Details) - USD ($) $ in Thousands	3 Months Ended								12 Months Ended
	Dec. 31, 2021	Sep. 30, 2021	Jun. 30, 2021	Mar. 31, 2021	Dec. 31, 2020	Sep. 30, 2020	Jun. 30, 2020	Mar. 31, 2020	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Accounts Receivable, Allowance for Credit Loss [Roll Forward]
Provision related to current period sales									$ 400	$ 200	$ 500
Total revenues	$ 401,332	$ 385,813	$ 442,408	$ 545,165	$ 494,676	$ 428,064	$ 301,207	$ 211,466	1,774,718	1,435,413	901,935
Rayaldee
Accounts Receivable, Allowance for Credit Loss [Roll Forward]
Beginning balance				11,737				11,786	11,737	11,786	4,043
Provision related to current period sales									37,265	52,391	42,528
Credits or payments made									(38,850)	(52,440)	(34,785)
Ending balance	10,152				11,737				10,152	11,737	11,786
Total revenues									$ 64,301	$ 88,187	$ 73,965
Provision for Rayaldee sales allowances and accruals as a percentage of gross Rayaldee sales (as a percent)									58.00%	58.00%	57.00%
Chargebacks, discounts, rebates and fees | Rayaldee
Accounts Receivable, Allowance for Credit Loss [Roll Forward]
Beginning balance				2,332				3,194	$ 2,332	$ 3,194	$ 1,316
Provision related to current period sales									14,426	17,604	13,723
Credits or payments made									(14,744)	(18,466)	(11,845)
Ending balance	2,014				2,332				2,014	2,332	3,194
Governmental | Rayaldee
Accounts Receivable, Allowance for Credit Loss [Roll Forward]
Beginning balance				5,812				5,841	5,812	5,841	2,090
Provision related to current period sales									21,553	32,721	25,106
Credits or payments made									(21,866)	(32,750)	(21,355)
Ending balance	5,499				5,812				5,499	5,812	5,841
Returns | Rayaldee
Accounts Receivable, Allowance for Credit Loss [Roll Forward]
Beginning balance				$ 3,593				$ 2,751	3,593	2,751	637
Provision related to current period sales									1,286	2,066	3,699
Credits or payments made									(2,240)	(1,224)	(1,585)
Ending balance	$ 2,639				$ 3,593				$ 2,639	$ 3,593	$ 2,751