Employee Benefit Plans (Details) - OPKO Health Savings and Retirement Plan - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Defined Contribution Plan Disclosure [Line Items]
Maximum annual contributions per employee (as a percent)	100.00%
Employer matching contribution (as a percent)	100.00%
Company's matching discretion on employee contributions to the Plan (as a percent)	4.00%
Employer discretionary contribution amount	$ 9.6	$ 8.3	$ 8.0