Debt Instrument, Convertible, Conversion Notice Threshold, Maximum

No definition available.

Name:	opk_DebtInstrumentConvertibleConversionNoticeThresholdMaximum
Namespace Prefix:	opk_
Data Type:	xbrli:durationItemType
Balance Type:	na
Period Type:	duration

- Definition

Debt Instrument, Convertible, Conversion Notice Threshold, Minimum

+ References

No definition available.

+ Details

Name:	opk_DebtInstrumentConvertibleConversionNoticeThresholdMinimum
Namespace Prefix:	opk_
Data Type:	xbrli:durationItemType
Balance Type:	na
Period Type:	duration

- Definition

Debt Instrument, Convertible Debt, Maximum Shares Issuable

+ References

No definition available.

+ Details

Name:	opk_DebtInstrumentConvertibleDebtMaximumSharesIssuable
Namespace Prefix:	opk_
Data Type:	xbrli:sharesItemType
Balance Type:	na
Period Type:	instant

- Definition

Number of financial institutions.

+ References

No definition available.

+ Details

Name:	opk_DebtInstrumentsNumberofFinancialInstitutions
Namespace Prefix:	opk_
Data Type:	xbrli:integerItemType
Balance Type:	na
Period Type:	instant

- Definition

Line of Credit Agreement, Intercompany Loan, Maximum

+ References

No definition available.

+ Details

Name:	opk_LineofCreditAgreementIntercompanyLoanMaximum
Namespace Prefix:	opk_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

- Definition

Line of Credit Facility, Covenant Terms, Total Revolving Commitment, Percentage

+ References

No definition available.

+ Details

Name:	opk_LineofCreditFacilityCovenantTermsTotalRevolvingCommitmentPercentage
Namespace Prefix:	opk_
Data Type:	num:percentItemType
Balance Type:	na
Period Type:	duration

- Definition

Line of Credit, Total Revolving Commitment, Threshold Consecutive Days

+ References

No definition available.

+ Details

Name:	opk_LineofCreditTotalRevolvingCommitmentThresholdConsecutiveDays
Namespace Prefix:	opk_
Data Type:	xbrli:durationItemType
Balance Type:	na
Period Type:	duration

- Definition

Proceeds From Convertible Debt, Conversion Fee

+ References

No definition available.

+ Details

Name:	opk_ProceedsFromConvertibleDebtConversionFee
Namespace Prefix:	opk_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

- Definition

The value of the financial instrument(s) that the original debt is being converted into in a noncash (or part noncash) transaction. "Part noncash" refers to that portion of the transaction not resulting in cash receipts or cash payments in the period.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 50
-Paragraph 3
-URI http://asc.fasb.org/extlink&oid=98513485&loc=d3e4304-108586

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 50
-Paragraph 5
-URI http://asc.fasb.org/extlink&oid=98513485&loc=d3e4332-108586

+ Details

Name:	us-gaap_DebtConversionConvertedInstrumentAmount1
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

- Definition

The number of shares issued in exchange for the original debt being converted in a noncash (or part noncash) transaction. "Part noncash" refers to that portion of the transaction not resulting in cash receipts or payments in the period.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 50
-Paragraph 5
-URI http://asc.fasb.org/extlink&oid=98513485&loc=d3e4332-108586

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 50
-Paragraph 3
-URI http://asc.fasb.org/extlink&oid=98513485&loc=d3e4304-108586

+ Details

Name:	us-gaap_DebtConversionConvertedInstrumentSharesIssued1
Namespace Prefix:	us-gaap_
Data Type:	xbrli:sharesItemType
Balance Type:	na
Period Type:	duration

- Definition

Percentage points added to the reference rate to compute the variable rate on the debt instrument.

+ References

No definition available.

+ Details

Name:	us-gaap_DebtInstrumentBasisSpreadOnVariableRate1
Namespace Prefix:	us-gaap_
Data Type:	num:percentItemType
Balance Type:	na
Period Type:	duration

- Definition

The carrying amount of the equity component of convertible debt which may be settled in cash upon conversion.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 470
-SubTopic 20
-Section 50
-Paragraph 4
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=109500613&loc=SL6031897-161870

+ Details

Name:	us-gaap_DebtInstrumentConvertibleCarryingAmountOfTheEquityComponent
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

The price per share of the conversion feature embedded in the debt instrument.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 470
-SubTopic 20
-Section 50
-Paragraph 5
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=109500613&loc=SL6031898-161870

+ Details

Name:	us-gaap_DebtInstrumentConvertibleConversionPrice1
Namespace Prefix:	us-gaap_
Data Type:	num:perShareItemType
Balance Type:	na
Period Type:	instant

- Definition

Ratio applied to the conversion of debt instrument into equity with equity shares divided by debt principal amount.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 505
-SubTopic 10
-Section 50
-Paragraph 7
-URI http://asc.fasb.org/extlink&oid=109259400&loc=d3e21521-112644

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 505
-SubTopic 10
-Section 50
-Paragraph 6
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=109259400&loc=d3e21506-112644

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.22(a)(5))
-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 505
-SubTopic 10
-Section 50
-Paragraph 3
-URI http://asc.fasb.org/extlink&oid=109259400&loc=d3e21475-112644

+ Details

Name:	us-gaap_DebtInstrumentConvertibleConversionRatio1
Namespace Prefix:	us-gaap_
Data Type:	xbrli:pureItemType
Balance Type:	na
Period Type:	duration

- Definition

Threshold period of specified consecutive trading days within which common stock price to conversion price of convertible debt instrument must exceed threshold percentage for specified number of trading days to trigger conversion feature.

+ References

No definition available.

+ Details

Name:	us-gaap_DebtInstrumentConvertibleThresholdConsecutiveTradingDays1
Namespace Prefix:	us-gaap_
Data Type:	xbrli:integerItemType
Balance Type:	na
Period Type:	duration

- Definition

Minimum percentage of common stock price to conversion price of convertible debt instruments to determine eligibility of conversion.

+ References

No definition available.

+ Details

Name:	us-gaap_DebtInstrumentConvertibleThresholdPercentageOfStockPriceTrigger
Namespace Prefix:	us-gaap_
Data Type:	num:percentItemType
Balance Type:	na
Period Type:	duration

- Definition

Threshold number of specified trading days that common stock price to conversion price of convertible debt instruments must exceed threshold percentage within a specified consecutive trading period to trigger conversion feature.

+ References

No definition available.

+ Details

Name:	us-gaap_DebtInstrumentConvertibleThresholdTradingDays
Namespace Prefix:	us-gaap_
Data Type:	xbrli:integerItemType
Balance Type:	na
Period Type:	duration

- Definition

Face (par) amount of debt instrument at time of issuance.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 835
-SubTopic 30
-Section 45
-Paragraph 2
-URI http://asc.fasb.org/extlink&oid=114775744&loc=d3e28551-108399

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 835
-SubTopic 30
-Section 55
-Paragraph 8
-URI http://asc.fasb.org/extlink&oid=114775985&loc=d3e28878-108400

+ Details

Name:	us-gaap_DebtInstrumentFaceAmount
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Effective interest rate for the funds borrowed under the debt agreement considering interest compounding and original issue discount or premium.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 470
-SubTopic 20
-Section 50
-Paragraph 6
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=109500613&loc=SL6036836-161870

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 835
-SubTopic 30
-Section 45
-Paragraph 2
-URI http://asc.fasb.org/extlink&oid=114775744&loc=d3e28551-108399

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.22(a)(1))
-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

+ Details

Name:	us-gaap_DebtInstrumentInterestRateEffectivePercentage
Namespace Prefix:	us-gaap_
Data Type:	num:percentItemType
Balance Type:	na
Period Type:	instant

- Definition

Contractual interest rate for funds borrowed, under the debt agreement.

+ References

+ Details

Name:	us-gaap_DebtInstrumentInterestRateStatedPercentage
Namespace Prefix:	us-gaap_
Data Type:	num:percentItemType
Balance Type:	na
Period Type:	instant

- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

+ Details

Name:	us-gaap_DebtInstrumentLineItems
Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration

- Definition

Percentage price of original principal amount of debt at which debt can be redeemed by the issuer.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 942
-SubTopic 470
-Section 50
-Paragraph 3
-Subparagraph e
-URI http://asc.fasb.org/extlink&oid=75038535&loc=d3e64711-112823

+ Details

Name:	us-gaap_DebtInstrumentRedemptionPricePercentage
Namespace Prefix:	us-gaap_
Data Type:	num:percentItemType
Balance Type:	na
Period Type:	duration

- Definition

Fair value amount of debt instrument that was repurchased.

+ References

No definition available.

+ Details

Name:	us-gaap_DebtInstrumentRepurchaseAmount
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	instant

- Definition

Period of time between issuance and maturity of debt instrument, in PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

+ References

No definition available.

+ Details

Name:	us-gaap_DebtInstrumentTerm
Namespace Prefix:	us-gaap_
Data Type:	xbrli:durationItemType
Balance Type:	na
Period Type:	duration

- Definition

Weighted average interest rate of debt outstanding.

+ References

No definition available.

+ Details

Name:	us-gaap_DebtWeightedAverageInterestRate
Namespace Prefix:	us-gaap_
Data Type:	num:percentItemType
Balance Type:	na
Period Type:	instant

- Definition

Amount after accumulated impairment loss of an asset representing future economic benefits arising from other assets acquired in a business combination that are not individually identified and separately recognized.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 350
-SubTopic 20
-Section 45
-Paragraph 5
-URI http://asc.fasb.org/extlink&oid=77989000&loc=SL49117168-202975

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 350
-SubTopic 20
-Section 45
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=99380562&loc=d3e13770-109266

+ Details

Name:	us-gaap_Goodwill
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	instant

- Definition

Sum of the carrying amounts of all intangible assets, excluding goodwill, as of the balance sheet date, net of accumulated amortization and impairment charges.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 350
-SubTopic 30
-Section 50
-Paragraph 2
-Subparagraph ((a)(1),(b))
-URI http://asc.fasb.org/extlink&oid=66006027&loc=d3e16323-109275

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 350
-SubTopic 30
-Section 45
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=6388964&loc=d3e16212-109274

+ Details

Name:	us-gaap_IntangibleAssetsNetExcludingGoodwill
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	instant

- Definition

Maximum borrowing capacity under the credit facility without consideration of any current restrictions on the amount that could be borrowed or the amounts currently outstanding under the facility.

+ References

+ Details

Name:	us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Amount of borrowing capacity currently available under the credit facility (current borrowing capacity less the amount of borrowings outstanding).

+ References

+ Details

Name:	us-gaap_LineOfCreditFacilityRemainingBorrowingCapacity
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

The fee, expressed as a percentage of the line of credit facility, for available but unused credit capacity under the credit facility.

+ References

No definition available.

+ Details

Name:	us-gaap_LineOfCreditFacilityUnusedCapacityCommitmentFeePercentage
Namespace Prefix:	us-gaap_
Data Type:	num:percentItemType
Balance Type:	na
Period Type:	duration

- Definition

Amount, after unamortized (discount) premium and debt issuance costs, of long-term debt. Includes, but not limited to, notes payable, bonds payable, debentures, mortgage loans and commercial paper. Excludes capital lease obligations.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 470
-SubTopic 20
-Section 50
-Paragraph 4
-Subparagraph (b)(3)
-URI http://asc.fasb.org/extlink&oid=109500613&loc=SL6031897-161870

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 944
-SubTopic 210
-Section S99
-Paragraph 1
-Subparagraph (SX 210.7-03(a)(16))
-URI http://asc.fasb.org/extlink&oid=119400593&loc=d3e572229-122910

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 942
-SubTopic 210
-Section S99
-Paragraph 1
-Subparagraph (SX 210.9-03(16))
-URI http://asc.fasb.org/extlink&oid=6876686&loc=d3e534808-122878

Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(22))
-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

+ Details

Name:	us-gaap_LongTermDebt
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

The interest rate applicable to the portion of the carrying amount of long-term borrowings outstanding as of the balance sheet date, including current maturities, which accrues interest at a rate subject to change from time to time.

+ References

+ Details

Name:	us-gaap_LongTermDebtPercentageBearingVariableInterestRate
Namespace Prefix:	us-gaap_
Data Type:	num:percentItemType
Balance Type:	na
Period Type:	instant

- Definition

The carrying value as of the balance sheet date of the noncurrent portion of long-term obligations drawn from a line of credit, which is a bank's commitment to make loans up to a specific amount. Examples of items that might be included in the application of this element may consist of letters of credit, standby letters of credit, and revolving credit arrangements, under which borrowings can be made up to a maximum amount as of any point in time conditional on satisfaction of specified terms before, as of and after the date of drawdowns on the line. Includes short-term obligations that would normally be classified as current liabilities but for which (a) postbalance sheet date issuance of a long term obligation to refinance the short term obligation on a long term basis, or (b) the enterprise has entered into a financing agreement that clearly permits the enterprise to refinance the short-term obligation on a long term basis and the following conditions are met (1) the agreement does not expire within 1 year and is not cancelable by the lender except for violation of an objectively determinable provision, (2) no violation exists at the BS date, and (3) the lender has entered into the financing agreement is expected to be financially capable of honoring the agreement.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.22)
-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 470
-SubTopic 10
-Section 45
-Paragraph 14
-URI http://asc.fasb.org/extlink&oid=99376301&loc=d3e1336-112600

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 470
-SubTopic 10
-Section 45
-Paragraph 13
-URI http://asc.fasb.org/extlink&oid=99376301&loc=d3e1314-112600

+ Details

Name:	us-gaap_LongTermLineOfCredit
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Amount of cash outflow for payment of an obligation from a lender, including but not limited to, letter of credit, standby letter of credit and revolving credit arrangements.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 15
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=118932676&loc=d3e3291-108585

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 235
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.4-08.(f))
-URI http://asc.fasb.org/extlink&oid=26873400&loc=d3e23780-122690

+ Details

Name:	us-gaap_RepaymentsOfLinesOfCredit
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

- Definition

Total of all stockholders' equity (deficit) items, net of receivables from officers, directors, owners, and affiliates of the entity which are attributable to the parent. The amount of the economic entity's stockholders' equity attributable to the parent excludes the amount of stockholders' equity which is allocable to that ownership interest in subsidiary equity which is not attributable to the parent (noncontrolling interest, minority interest). This excludes temporary equity and is sometimes called permanent equity.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 310
-SubTopic 10
-Section S99
-Paragraph 2
-Subparagraph (SAB Topic 4.E)
-URI http://asc.fasb.org/extlink&oid=27010918&loc=d3e74512-122707

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(31))
-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(29))
-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(30))
-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

+ Details

Name:	us-gaap_StockholdersEquity
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Details

Name:	us-gaap_BusinessAcquisitionAxis=opk_BioReferenceMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_BusinessAcquisitionAxis=opk_OPKOHealthEuropeMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	srt_RangeAxis=srt_MinimumMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	srt_RangeAxis=srt_MaximumMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_LongtermDebtTypeAxis=us-gaap_ConvertibleNotesPayableMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentAxis=opk_NotesDueFebruary12033Member
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_LongtermDebtTypeAxis=us-gaap_ConvertibleDebtMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentAxis=opk_ConvertibleSeniorNotesDue2025Member
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentRedemptionPeriodAxis=us-gaap_DebtInstrumentRedemptionPeriodOneMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentRedemptionPeriodAxis=us-gaap_DebtInstrumentRedemptionPeriodTwoMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentRedemptionPeriodAxis=us-gaap_DebtInstrumentRedemptionPeriodThreeMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentAxis=opk_A5ConvertibleNotesMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_LongtermDebtTypeAxis=us-gaap_LineOfCreditMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_StatementClassOfStockAxis=us-gaap_CommonStockMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_CreditFacilityAxis=us-gaap_LineOfCreditMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_LongtermDebtTypeAxis=us-gaap_UnsecuredDebtMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_CreditFacilityAxis=us-gaap_RevolvingCreditFacilityMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentAxis=opk_NewCreditAgreementMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_CreditFacilityAxis=us-gaap_BridgeLoanMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_CreditFacilityAxis=us-gaap_LetterOfCreditMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_VariableRateAxis=us-gaap_LondonInterbankOfferedRateLIBORMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_VariableRateAxis=opk_LondonInterbankOfferedRateLIBORFirstTwelveMonthsMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_VariableRateAxis=opk_LondonInterbankOfferedRateLIBORThereafterMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_VariableRateAxis=opk_LondonInterbankOfferedRateLIBORFirstTwelveMonthsAdjustedforEurocurrencyLiabilitiesMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_VariableRateAxis=opk_LondonInterbankOfferedRateLIBORThereafterAdjustedforEurocurrencyLiabilitiesMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_RelatedPartyTransactionsByRelatedPartyAxis=opk_DrFrostMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

Debt - Narrative (Details)						1 Months Ended			3 Months Ended	12 Months Ended			48 Months Ended
Debt - Narrative (Details)	Feb. 20, 2019 USD ($)	Dec. 22, 2017 USD ($)	Aug. 07, 2017 USD ($)	Mar. 17, 2017 USD ($)	Nov. 05, 2015 USD ($)	Feb. 28, 2019 USD ($)	Feb. 28, 2018 USD ($) $ / shares	Jan. 31, 2013 USD ($)	Sep. 30, 2019	Dec. 31, 2019 USD ($) day institution $ / shares shares	Dec. 31, 2018 USD ($)	Dec. 31, 2017 USD ($)	Dec. 31, 2016 USD ($) shares	Nov. 04, 2019 USD ($)	Feb. 01, 2019 USD ($)	Nov. 08, 2018 USD ($)	Nov. 30, 2015 USD ($)
Debt Instrument [Line Items]
Credit line capacity										$ 97,756,000
Repayments of line of credit										359,322,000	$ 34,681,000	$ 33,510,000
Line of credit										44,749,000	105,198,000
Net assets										1,614,759,000	1,791,291,000	1,843,623,000	$ 2,046,433,000
Goodwill										$ 671,940,000	$ 700,193,000	$ 717,099,000
Number of financial institutions \| institution										11
BioReference Laboratories, Inc.
Debt Instrument [Line Items]
Net assets										$ 885,200,000
Goodwill										434,800,000
Intangible assets										$ 365,700,000
OPKO Health Europe
Debt Instrument [Line Items]
Weighted average interest rate (as a percent)										2.70%	2.10%
Minimum
Debt Instrument [Line Items]
Total revolving commitment, minimum consecutive days									30 days	30 days
Minimum \| OPKO Health Europe
Debt Instrument [Line Items]
Variable interest rates (as a percent)										1.00%
Maximum
Debt Instrument [Line Items]
Total revolving commitment (as a percent)									10.00%	10.00%
Maximum \| OPKO Health Europe
Debt Instrument [Line Items]
Variable interest rates (as a percent)										3.80%
Notes \| Notes Due February 1, 2033
Debt Instrument [Line Items]
Debt face amount								$ 175,000,000.0
Interest rate of notes payable								3.00%
Equivalent redemption price								100.00%
Debt repurchase amount															$ 28,800,000
Long term debt															$ 3,000,000.0
Convertible Debt
Debt Instrument [Line Items]
Interest rate of notes payable						4.50%
Convertible Debt \| Convertible Senior Notes Due 2025
Debt Instrument [Line Items]
Debt face amount						$ 200,000,000.0
Conversion ratio						0.2367
Conversion price (in dollars per share) \| $ / shares										$ 4.22
Maximum shares of common stock to be loaned to affiliates \| shares										30,000,000
Convertible debt, stock issued from conversion (in shares) \| shares										29,250,000
One-time nominal fee for newly issued shares										$ 300,000
Valuation of equity component at issue date										$ 52,600,000
Effective interest rate (as a percent)										11.20%
Convertible Debt \| Convertible Senior Notes Due 2025 \| On or after February 1, 2017 and before February 1, 2019
Debt Instrument [Line Items]
Convertible debt, threshold percentage of stock price trigger										130.00%
Equivalent redemption price										100.00%
Convertible Debt \| Convertible Senior Notes Due 2025 \| On or after February 1, 2017 and before February 1, 2019 \| Minimum
Debt Instrument [Line Items]
Threshold trading days \| day										20
Convertible Debt \| Convertible Senior Notes Due 2025 \| On or after February 1, 2017 and before February 1, 2019 \| Maximum
Debt Instrument [Line Items]
Number of consecutive trading days applicable conversion price \| day										30
Convertible Debt \| Convertible Senior Notes Due 2025 \| Prior to November 15, 2024
Debt Instrument [Line Items]
Convertible debt, threshold percentage of stock price trigger										98.00%
Convertible Debt \| Convertible Senior Notes Due 2025 \| Prior to November 15, 2024 \| Minimum
Debt Instrument [Line Items]
Threshold trading days \| day										5
Convertible Debt \| Convertible Senior Notes Due 2025 \| Prior to November 15, 2024 \| Maximum
Debt Instrument [Line Items]
Number of consecutive trading days applicable conversion price \| day										5
Convertible Debt \| Convertible Senior Notes Due 2025 \| On Or After February 15, 2022
Debt Instrument [Line Items]
Convertible debt, threshold percentage of stock price trigger										130.00%
Equivalent redemption price										100.00%
Convertible Debt \| Convertible Senior Notes Due 2025 \| On Or After February 15, 2022 \| Minimum
Debt Instrument [Line Items]
Threshold trading days \| day										20
Convertible Debt \| Convertible Senior Notes Due 2025 \| On Or After February 15, 2022 \| Maximum
Debt Instrument [Line Items]
Number of consecutive trading days applicable conversion price \| day										30
Convertible Debt \| 5% Convertible Notes
Debt Instrument [Line Items]
Debt face amount							$ 55,000,000.0
Interest rate of notes payable							5.00%
Conversion price (in dollars per share) \| $ / shares							$ 5.00
Note maturity term (in years)							5 years
Conversion notice threshold minimum (in days)							30 days
Conversion notice threshold maximum (in days)							60 days
Convertible Debt \| Notes Due February 1, 2033
Debt Instrument [Line Items]
Convertible notes, conversion													$ 143,200,000
Line of Credit
Debt Instrument [Line Items]
Weighted average interest rate (as a percent)										4.00%	4.70%
Equity securities \| Convertible Debt \| Notes Due February 1, 2033
Debt Instrument [Line Items]
Convertible debt, stock issued from conversion (in shares) \| shares													21,539,873
Line of Credit \| Unsecured Debt
Debt Instrument [Line Items]
Interest rate of notes payable																10.00%
Credit line capacity																$ 60,000,000
Revolving Credit Facility \| Line of Credit \| New Credit Agreement
Debt Instrument [Line Items]
Credit line capacity					$ 75,000,000.0									$ 75,000,000			$ 100,000,000
Remaining borrowing capacity										$ 6,200,000
Commitment fee percentage					0.25%
Intercompany loan maximum borrowing capacity		$ 45,000,000.0	$ 35,000,000.0	$ 55,000,000.0
Bridge Loan \| Line of Credit \| New Credit Agreement
Debt Instrument [Line Items]
Credit line capacity					$ 20,000,000.0
Letter of Credit \| Line of Credit \| New Credit Agreement
Debt Instrument [Line Items]
Credit line capacity					$ 20,000,000.0
LIBOR \| Revolving Credit Facility \| Line of Credit \| New Credit Agreement
Debt Instrument [Line Items]
Estimated credit spread (as a percent)					2.50%
LIBOR, First 12 Months \| Revolving Credit Facility \| Line of Credit \| New Credit Agreement
Debt Instrument [Line Items]
Estimated credit spread (as a percent)					0.35%
LIBOR, Thereafter \| Revolving Credit Facility \| Line of Credit \| New Credit Agreement
Debt Instrument [Line Items]
Estimated credit spread (as a percent)					0.50%
LIBOR, First 12 Months, Adjusted for Eurocurrency Liabilities \| Revolving Credit Facility \| Line of Credit \| New Credit Agreement
Debt Instrument [Line Items]
Estimated credit spread (as a percent)					1.35%
LIBOR, Thereafter, Adjusted for Eurocurrency Liabilities \| Revolving Credit Facility \| Line of Credit \| New Credit Agreement
Debt Instrument [Line Items]
Estimated credit spread (as a percent)					1.50%
Dr Frost \| Line of Credit \| Unsecured Debt
Debt Instrument [Line Items]
Repayments of line of credit	$ 28,800,000