Segments - Operations and Assets Information (Details) - USD ($) $ in Thousands	3 Months Ended	12 Months Ended
Mar. 31, 2018	Mar. 31, 2017	Dec. 31, 2017
Segment Reporting Information [Line Items]
Revenue from services	$ 211,315	$ 228,545	$ 228,545
Revenue from products	27,851	22,231
Revenue from transfer of intellectual property and other	15,748	15,606	15,606
Operating loss	(42,611)	(45,215)
Depreciation and amortization	24,757	25,730
Net income (loss) from investment in investees	(2,456)	(2,131)
Revenues	254,914	266,382
Assets	2,578,894		2,589,956
Goodwill	719,891		717,099
United States
Segment Reporting Information [Line Items]
Revenues	215,311	229,436
Ireland
Segment Reporting Information [Line Items]
Revenues	17,282	17,209
Chile
Segment Reporting Information [Line Items]
Revenues	11,733	10,121
Spain
Segment Reporting Information [Line Items]
Revenues	5,532	4,505
Israel
Segment Reporting Information [Line Items]
Revenues	3,614	4,217
Mexico
Segment Reporting Information [Line Items]
Revenues	1,420	865
Other
Segment Reporting Information [Line Items]
Revenues	22	29
Corporate
Segment Reporting Information [Line Items]
Revenue from services	0	0
Revenue from transfer of intellectual property and other	0	0
Operating loss	(11,645)	(15,970)
Depreciation and amortization	30	30
Net income (loss) from investment in investees	0	0
Assets	58,750		60,604
Goodwill	0		0
Pharmaceutical \| Operating Segments
Segment Reporting Information [Line Items]
Revenue from services	0	0
Revenue from products	27,851	22,231
Revenue from transfer of intellectual property and other	15,748	15,606
Operating loss	(22,948)	(26,145)
Depreciation and amortization	6,740	6,775
Net income (loss) from investment in investees	(2,172)	(1,814)
Assets	1,294,067		1,287,964
Goodwill	267,104		264,313
Diagnostics \| Operating Segments
Segment Reporting Information [Line Items]
Revenue from services	211,315	228,545
Revenue from transfer of intellectual property and other	0	0
Operating loss	(8,018)	(3,100)
Depreciation and amortization	17,987	18,925
Net income (loss) from investment in investees	(284)	$ (317)
Assets	1,226,077		1,241,388
Goodwill	$ 452,787		$ 452,786

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- Definition

Sum of the carrying amounts as of the balance sheet date of all assets that are recognized. Assets are probable future economic benefits obtained or controlled by an entity as a result of past transactions or events.

+ References

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-Publisher FASB
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The aggregate expense recognized in the current period that allocates the cost of tangible assets, intangible assets, or depleting assets to periods that benefit from use of the assets.

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This item represents the net total realized and unrealized gain (loss) included in earnings for the period as a result of selling or holding marketable securities categorized as trading, available-for-sale, or held-to-maturity, including the unrealized holding gain (loss) of held-to-maturity securities transferred to the trading security category and the cumulative unrealized gain (loss) which was included in other comprehensive income (a separate component of shareholders' equity) for available-for-sale securities transferred to trading securities during the period. Additionally, this item would include any gains (losses) realized during the period from the sale of investments accounted for under the cost method of accounting and losses recognized for other than temporary impairments (OTTI) of the subject investments.

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- Definition

Amount after accumulated impairment loss of an asset representing future economic benefits arising from other assets acquired in a business combination that are not individually identified and separately recognized.

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The net result for the period of deducting operating expenses from operating revenues.

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- Definition

Aggregate revenue during the period from the sale of goods in the normal course of business, after deducting returns, allowances and discounts.

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Total revenue from sale of goods and services rendered during the reporting period, in the normal course of business, reduced by sales returns and allowances, and sales discounts.

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Aggregate revenue during the period from services rendered in the normal course of business, after deducting allowances and discounts.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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