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Revenue Recognition - Schedule of Product Sales Allowances and Accruals (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Allowance for Doubtful Accounts Receivable [Roll Forward]    
Provision related to current period sales $ 100 $ 900
Rayaldee    
Allowance for Doubtful Accounts Receivable [Roll Forward]    
Beginning balance 1,018  
Provision related to current period sales 2,230  
Credits or payments made (1,945)  
Ending balance 1,303  
Total gross Rayaldee sales $ 5,922  
Provision for Rayaldee sales allowances and accruals as a percentage of gross Rayaldee sales 38.00%  
Chargebacks, discounts, rebates and fees | Rayaldee    
Allowance for Doubtful Accounts Receivable [Roll Forward]    
Beginning balance $ 233  
Provision related to current period sales 961  
Credits or payments made (805)  
Ending balance 389  
Governmental | Rayaldee    
Allowance for Doubtful Accounts Receivable [Roll Forward]    
Beginning balance 348  
Provision related to current period sales 1,339  
Credits or payments made (955)  
Ending balance 732  
Returns | Rayaldee    
Allowance for Doubtful Accounts Receivable [Roll Forward]    
Beginning balance 437  
Provision related to current period sales (70)  
Credits or payments made (185)  
Ending balance $ 182