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Equity Security, FV-NI, Ownership Percentage

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Operating Leases, Monthly Payments, Year One

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Related Party Transaction, Future Contributions

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Area of a real estate property.

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- Definition

Number of securities into which the class of warrant or right may be converted. For example, but not limited to, 500,000 warrants may be converted into 1,000,000 shares.

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The number of equity instruments that the holder of the debt instrument would receive if the debt was converted to equity.

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Face (par) amount of debt instrument at time of issuance.

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- Definition

The percentage of ownership of common stock or equity participation in the investee accounted for under the equity method of accounting.

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The cash outflow to acquire debt and equity securities not classified as either held-to-maturity securities or trading securities which would be classified as available-for-sale securities and reported at fair value, with unrealized gains and losses excluded from earnings and reported in a separate component of shareholders' equity.

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The cash outflow associated with the purchase of or advances to an equity method investments, which are investments in joint ventures and entities in which the entity has an equity ownership interest normally of 20 to 50 percent and exercises significant influence.

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Expenses recognized resulting from transactions (excluding transactions that are eliminated in consolidated or combined financial statements) with related party.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Percentage of the Variable Interest Entity's (VIE) voting interest owned by (or beneficial interest in) the reporting entity (directly or indirectly).

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Related Party Transactions (Details)	1 Months Ended						3 Months Ended
Related Party Transactions (Details)	Feb. 28, 2018 USD ($) shares	Nov. 30, 2017 USD ($) shares	Jul. 31, 2017 USD ($) shares	May 31, 2017 USD ($) shares	Apr. 30, 2017 USD ($) shares	Aug. 31, 2016 USD ($) shares	Mar. 31, 2018 USD ($) shares	Mar. 31, 2017 USD ($)	Jan. 01, 2017 USD ($) ft²	Nov. 30, 2016 USD ($)
Zebra
Related Party Transaction [Line Items]
Stock ownership percentage							29.00%
Equity method investment, ownership percentage							29.00%
Neovasc
Related Party Transaction [Line Items]
Equity method investment, ownership percentage							1.00%
Additional investment in equity method investment \| $		$ 3,000,000
Number of shares into which warrants may be converted (in shares)							4,900,000
ChromaDex Corporation
Related Party Transaction [Line Items]
Ownership percentage							0.00%
MabVax
Related Party Transaction [Line Items]
Ownership percentage							2.00%
Available-for-sale investment, additional investment in period \| $			$ 100,000	$ 500,000
COCP
Related Party Transaction [Line Items]
Equity method investment, ownership percentage							9.00%
Additional investment in equity method investment \| $					$ 1,000,000	$ 2,000,000
Number of shares into which warrants may be converted (in shares)							1,000,000
InCellDx, Inc
Related Party Transaction [Line Items]
Equity method investment, ownership percentage							29.00%
Number of shares into which warrants may be converted (in shares)							700,000
BioCardia, Inc.
Related Party Transaction [Line Items]
Equity method investment, ownership percentage							5.00%
Ownership percentage							5.00%
Number of shares into which warrants may be converted (in shares)							400,000
NIMS
Related Party Transaction [Line Items]
Ownership percentage							1.00%
Frost Real Estate Holdings LLC
Related Party Transaction [Line Items]
Area of real estate property (in square feet) \| ft²									29,500
Lease payments per month in first year \| $									$ 81,000
Lease payments per month in third year \| $									$ 86,000
Reimbursement Of Travel Expense \| Dr Frost
Related Party Transaction [Line Items]
Reimbursement paid to related party for travel \| $							$ 79,000	$ 20,000
Common Stock \| Neovasc
Related Party Transaction [Line Items]
Equity method investment, additional investment in period (in shares)		2,054,794
Common Stock \| COCP
Related Party Transaction [Line Items]
Equity method investment, additional investment in period (in shares)					138,889	162,602
Series G Preferred Stock \| MabVax
Related Party Transaction [Line Items]
Available-for-sale investment, additional investment in period (in shares)			50,714
Series L Preferred Stock \| MabVax
Related Party Transaction [Line Items]
Available-for-sale investment, additional investment in period (in shares)				1,667
Series I Preferred Stock \| MabVax
Related Party Transaction [Line Items]
Available-for-sale investment, additional investment in period (in shares)				107,607
Museum of Science, Inc \| Dr Frost and Mr Pfenniger
Related Party Transaction [Line Items]
Related party future contribution \| $										$ 1,000,000
Convertible Debt \| COCP
Related Party Transaction [Line Items]
Additional investment in equity method investment \| $	$ 1,000,000
Convertible Debt \| Common Stock \| COCP
Related Party Transaction [Line Items]
Shares issues upon conversion (in shares)	123,456
5% Convertible Notes \| Convertible Debt
Related Party Transaction [Line Items]
Debt face amount \| $	$ 55,000,000.0
Series A Warrant \| Neovasc
Related Party Transaction [Line Items]
Number of shares into which warrants may be converted (in shares)		2,054,794
Series B Warrant \| Neovasc
Related Party Transaction [Line Items]
Number of shares into which warrants may be converted (in shares)		2,054,794
Series C Warrant \| Neovasc
Related Party Transaction [Line Items]
Number of shares into which warrants may be converted (in shares)		822,192