Acquisitions, Investments and Licenses - Equity and Cost Method Investments Narrative (Details) $ in Millions	3 Months Ended
	Mar. 31, 2018 USD ($)
Schedule of Equity Method Investments [Line Items]
Total assets of equity method investees	$ 382.2
Total (liabilities) of equity method investees	(142.7)
Net (losses) of equity method investees	(20.8)
Market value	$ 43.8
Pharmsynthez
Schedule of Equity Method Investments [Line Items]
Ownership percentage, equity method	9.00%
Cocrystal
Schedule of Equity Method Investments [Line Items]
Ownership percentage, equity method	9.00%
Non-Invasive Monitoring Systems, Inc.
Schedule of Equity Method Investments [Line Items]
Ownership percentage, equity method	1.00%
Neovasc
Schedule of Equity Method Investments [Line Items]
Ownership percentage, equity method	1.00%
VBI Vaccines Inc
Schedule of Equity Method Investments [Line Items]
Ownership percentage, equity method	10.40%
InCellDx, Inc
Schedule of Equity Method Investments [Line Items]
Ownership percentage, equity method	29.00%
BioCardia, Inc.
Schedule of Equity Method Investments [Line Items]
Ownership percentage, equity method	5.00%
Xenetic Biosciences, Inc.
Schedule of Equity Method Investments [Line Items]
Ownership percentage, equity method	4.00%