Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2018	Dec. 31, 2017
Current assets:
Cash and cash equivalents	$ 99,943	$ 91,499
Accounts receivable, net	158,642	165,516
Inventory, net	49,815	49,333
Other current assets and prepaid expenses	40,946	42,513
Total current assets	349,346	348,861
Property, plant and equipment, net	148,718	146,557
Intangible assets, net	667,637	683,835
In-process research and development	646,386	647,347
Goodwill	719,891	717,099
Investments	41,289	40,642
Other assets	5,627	5,615
Total assets	2,578,894	2,589,956
Current liabilities:
Accounts payable	64,229	74,307
Accrued expenses	217,133	230,301
Current portion of 2033 Senior Notes	29,744	0
Current portion of lines of credit and notes payable	6,971	11,926
Total current liabilities	318,077	316,534
2023 Convertible Notes and 2033 Senior Notes	55,199	29,160
Deferred tax liabilities, net	148,732	148,729
Other long-term liabilities, principally contract liabilities, contingent consideration and line of credit	233,622	239,955
Total long-term liabilities	437,553	417,844
Total liabilities	755,630	734,378
Equity:
Common Stock - $0.01 par value, 750,000,000 shares authorized; 560,023,745 and 560,023,745 shares issued at March 31, 2018 and December 31, 2017, respectively	5,600	5,600
Treasury Stock - 549,907 and 549,907 shares at March 31, 2018 and December 31, 2017, respectively	(1,791)	(1,791)
Additional paid-in capital	2,895,191	2,889,256
Accumulated other comprehensive loss	(539)	(528)
Accumulated deficit	(1,075,197)	(1,036,959)
Total shareholders’ equity	1,823,264	1,855,578
Total liabilities and equity	$ 2,578,894	$ 2,589,956