<SEC-DOCUMENT>0000944809-17-000011-index.html : 20170920
<SEC-HEADER>0000944809-17-000011.hdr.sgml : 20170920
<ACCEPTANCE-DATETIME>20170920155357
ACCESSION NUMBER:		0000944809-17-000011
CONFORMED SUBMISSION TYPE:	SC 13D/A
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20170920
DATE AS OF CHANGE:		20170920

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Opko Health, Inc.
		CENTRAL INDEX KEY:			0000944809
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				752402409
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13D/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-51671
		FILM NUMBER:		171094042

	BUSINESS ADDRESS:	
		STREET 1:		4400 BISCAYNE BLVD.
		CITY:			MIAMI
		STATE:			FL
		ZIP:			33137
		BUSINESS PHONE:		305-575-4138

	MAIL ADDRESS:	
		STREET 1:		4400 BISCAYNE BLVD.
		CITY:			MIAMI
		STATE:			FL
		ZIP:			33137

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	eXegenics Inc
		DATE OF NAME CHANGE:	20040505

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	EXEGENICS INC
		DATE OF NAME CHANGE:	20011114

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CYTOCLONAL PHARMACEUTICS INC /DE
		DATE OF NAME CHANGE:	19950503

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Opko Health, Inc.
		CENTRAL INDEX KEY:			0000944809
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				752402409
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13D/A

	BUSINESS ADDRESS:	
		STREET 1:		4400 BISCAYNE BLVD.
		CITY:			MIAMI
		STATE:			FL
		ZIP:			33137
		BUSINESS PHONE:		305-575-4138

	MAIL ADDRESS:	
		STREET 1:		4400 BISCAYNE BLVD.
		CITY:			MIAMI
		STATE:			FL
		ZIP:			33137

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	eXegenics Inc
		DATE OF NAME CHANGE:	20040505

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	EXEGENICS INC
		DATE OF NAME CHANGE:	20011114

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CYTOCLONAL PHARMACEUTICS INC /DE
		DATE OF NAME CHANGE:	19950503
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13D/A
<SEQUENCE>1
<FILENAME>schedule13d-frostamend159x.htm
<DESCRIPTION>SC 13D/A
<TEXT>
Document 1 - file: schedule13d-frostamend159x.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-1
<SEQUENCE>2
<FILENAME>exhibit1tofrostamendment15.htm
<DESCRIPTION>EXHIBIT 1
<TEXT>
Document 2 - file: exhibit1tofrostamendment15.htm

</DOCUMENT>
</SEC-DOCUMENT>