Segments - Operations and Assets Information (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2017	Jun. 30, 2016	Jun. 30, 2017	Jun. 30, 2016	Dec. 31, 2016
Segment Reporting Information [Line Items]
Revenue from services	$ 256,671	$ 266,012	$ 511,956	$ 518,534
Product revenues	28,966	22,807	51,197	42,706
Revenue from transfer of intellectual property and other	28,576	68,281	47,154	86,898
Operating income (loss)	(26,443)	28,266	(68,151)	748
Depreciation and amortization	25,551	24,580	51,281	46,780
Net income (loss) from investment in investees	(5,628)	(1,988)	(7,758)	(4,333)
Revenues	314,213	357,100	610,307	648,138
Assets	2,768,694		2,768,694		$ 2,766,619
Goodwill	712,075		712,075		704,603
United States
Segment Reporting Information [Line Items]
Revenues	266,874	266,044	522,514	518,482
Ireland
Segment Reporting Information [Line Items]
Revenues	21,913	71,789	42,630	93,932
Chile
Segment Reporting Information [Line Items]
Revenues	11,899	9,597	22,020	16,580
Spain
Segment Reporting Information [Line Items]
Revenues	5,118	4,324	9,623	8,347
Israel
Segment Reporting Information [Line Items]
Revenues	7,654	4,420	11,872	9,162
Mexico
Segment Reporting Information [Line Items]
Revenues	724	926	1,589	1,635
Other
Segment Reporting Information [Line Items]
Revenues	31	0	59	0
Corporate
Segment Reporting Information [Line Items]
Revenue from services	0	0	0	0
Revenue from transfer of intellectual property and other	0	0	0	0
Operating income (loss)	(12,878)	(17,453)	(28,849)	(41,286)
Depreciation and amortization	30	20	60	39
Net income (loss) from investment in investees	0	0	0	0
Assets	93,200		93,200		63,181
Goodwill	0		0		0
Pharmaceutical | Operating Segments
Segment Reporting Information [Line Items]
Revenue from services	0	0	0	0
Product revenues	28,966	22,807	51,197	42,706
Revenue from transfer of intellectual property and other	28,576	68,281	47,154	86,898
Operating income (loss)	(8,621)	35,345	(31,258)	34,015
Depreciation and amortization	6,694	2,987	13,469	5,848
Net income (loss) from investment in investees	(5,309)	391	(7,123)	(4,430)
Assets	1,294,645		1,294,645		1,294,916
Goodwill	259,288		259,288		251,817
Diagnostics | Operating Segments
Segment Reporting Information [Line Items]
Revenue from services	256,671	266,012	511,956	518,534
Revenue from transfer of intellectual property and other	0	0	0	0
Operating income (loss)	(4,944)	10,374	(8,044)	8,019
Depreciation and amortization	18,827	21,573	37,752	40,893
Net income (loss) from investment in investees	(319)	$ (2,379)	(635)	$ 97
Assets	1,380,849		1,380,849		1,408,522
Goodwill	$ 452,787		$ 452,787		$ 452,786