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Summary of Significant Accounting Policies (Details)
$ in Thousands
3 Months Ended 6 Months Ended 12 Months Ended
Jan. 01, 2016
Dec. 31, 2015
Jun. 30, 2017
USD ($)
Jun. 30, 2016
USD ($)
Jun. 30, 2017
USD ($)
Segment
Jun. 30, 2016
USD ($)
Dec. 31, 2016
USD ($)
Mar. 31, 2016
USD ($)
Summary of Significant Accounting Policies [Line Items]                
Provision for inventory obsolescence         $ 4,800 $ 200    
Goodwill, in-process research and development and other intangible assets acquired     $ 2,100,000   2,100,000   $ 2,100,000  
In-process research and development     645,957   645,957   644,713  
Amortization expense     17,953 $ 15,778 35,881 29,221    
Intangible assets, net     731,134   731,134   763,976  
Depreciation expense         15,400 17,600    
Deferred revenue     128,500   128,500   162,400  
Revenue from transfer of intellectual property and other     28,576 68,281 47,154 86,898    
Allowance for doubtful accounts receivable     55,220   55,220   $ 36,268  
Provision for bad debts         50,000 40,500    
Equity-based compensation expense         $ 15,844 26,105    
Number of reportable segments | Segment         2      
Minimum                
Summary of Significant Accounting Policies [Line Items]                
Intangible assets, estimated useful lives         3 years      
Maximum                
Summary of Significant Accounting Policies [Line Items]                
Intangible assets, estimated useful lives         20 years      
Government Contracts Concentration Risk | Sales Revenue, Net                
Summary of Significant Accounting Policies [Line Items]                
Concentration percentage         26.00%      
Government Contracts Concentration Risk | Accounts Receivable                
Summary of Significant Accounting Policies [Line Items]                
Concentration percentage         20.70%   22.90%  
Software                
Summary of Significant Accounting Policies [Line Items]                
Property, plant and equipment, estimated useful lives         3 years      
Machinery, Medical and Other Equipment | Minimum                
Summary of Significant Accounting Policies [Line Items]                
Property, plant and equipment, estimated useful lives         5 years      
Machinery, Medical and Other Equipment | Maximum                
Summary of Significant Accounting Policies [Line Items]                
Property, plant and equipment, estimated useful lives         8 years      
Furniture and Fixtures | Minimum                
Summary of Significant Accounting Policies [Line Items]                
Property, plant and equipment, estimated useful lives         5 years      
Furniture and Fixtures | Maximum                
Summary of Significant Accounting Policies [Line Items]                
Property, plant and equipment, estimated useful lives         12 years      
Buildings and Improvements | Minimum                
Summary of Significant Accounting Policies [Line Items]                
Property, plant and equipment, estimated useful lives         10 years      
Buildings and Improvements | Maximum                
Summary of Significant Accounting Policies [Line Items]                
Property, plant and equipment, estimated useful lives         40 years      
Automobiles and Aircraft | Minimum                
Summary of Significant Accounting Policies [Line Items]                
Property, plant and equipment, estimated useful lives         3 years      
Automobiles and Aircraft | Maximum                
Summary of Significant Accounting Policies [Line Items]                
Property, plant and equipment, estimated useful lives         15 years      
Collaborative Arrangement, Product | Pfizer                
Summary of Significant Accounting Policies [Line Items]                
Deferred revenue     123,600   $ 123,600      
Revenue from transfer of intellectual property and other     $ 17,700 17,700 $ 35,300      
Self-Pay | Accounts Receivable                
Summary of Significant Accounting Policies [Line Items]                
Concentration percentage         6.30%   4.10%  
Internal Revenue Service (IRS)                
Summary of Significant Accounting Policies [Line Items]                
Corporate income tax rate     35.00%   35.00%      
Israel Tax Authority                
Summary of Significant Accounting Policies [Line Items]                
Corporate income tax rate 24.00% 25.00%     23.00%      
Scenario, Adjustment                
Summary of Significant Accounting Policies [Line Items]                
In-process research and development       (187,600)   (187,600)    
Intangible assets, net       $ 187,600   $ 187,600    
In-process Research and Development                
Summary of Significant Accounting Policies [Line Items]                
Intangible assets, estimated useful lives           12 years    
Rayaldee                
Summary of Significant Accounting Policies [Line Items]                
Deferred revenue     $ 3,700   $ 3,700      
Accounting Standards Update 2016-09, Excess Tax Benefit Component                
Summary of Significant Accounting Policies [Line Items]                
Deferred tax asset               $ 32,500
Accumulated Deficit | Accounting Standards Update 2016-09, Excess Tax Benefit Component                
Summary of Significant Accounting Policies [Line Items]                
Cumulative effect of new accounting update               $ (32,500)