Available-for-Sale Securities, Ownership Percentage

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Operating Leases, Monthly Payments, Year Five

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Operating Leases, Monthly Payments, Year One

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Tenant Improvements, Offset Against Operating Lease in Next Twelve Months

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- Definition

Area of a real estate property.

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- Definition

Number of securities into which the class of warrant or right may be converted. For example, but not limited to, 500,000 warrants may be converted into 1,000,000 shares.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 235
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.4-08.(i)(2))
-URI http://asc.fasb.org/extlink&oid=26873400&loc=d3e23780-122690

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- Definition

The percentage of ownership of common stock or equity participation in the investee accounted for under the equity method of accounting.

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 323
-SubTopic 10
-Section 50
-Paragraph 3
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- Definition

Balance held at close of period in number of shares.

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 946
-SubTopic 320
-Section S99
-Paragraph 4
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- Definition

The cash outflow to acquire debt and equity securities not classified as either held-to-maturity securities or trading securities which would be classified as available-for-sale securities and reported at fair value, with unrealized gains and losses excluded from earnings and reported in a separate component of shareholders' equity.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Glossary Investing Activities
-URI http://asc.fasb.org/extlink&oid=6516133

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
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The cash outflow associated with the purchase of or advances to an equity method investments, which are investments in joint ventures and entities in which the entity has an equity ownership interest normally of 20 to 50 percent and exercises significant influence.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 13
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=66902209&loc=d3e3213-108585

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- Definition

Expenses recognized resulting from transactions (excluding transactions that are eliminated in consolidated or combined financial statements) with related party.

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 850
-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (c)
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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Price of a single share of a number of saleable stocks of a company.

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Related Party Transactions (Details) $ / shares in Units, ft² in Thousands, $ in Thousands	1 Months Ended				3 Months Ended		6 Months Ended
	Jan. 31, 2016 USD ($) shares	Nov. 30, 2015 USD ($) shares	Oct. 31, 2015 USD ($) $ / shares shares	Jul. 31, 2015 USD ($) shares	Jun. 30, 2016 USD ($) $ / shares shares	Jun. 30, 2015 USD ($)	Jun. 30, 2016 USD ($) $ / shares shares	Jun. 30, 2015 USD ($)	Aug. 31, 2015 $ / shares	May 31, 2015 $ / shares	May 28, 2015 USD ($) ft²
Zebra
Related Party Transaction [Line Items]
Equity method investment, ownership percentage					29.00%		29.00%
Additional investment \| $		$ 1,000
Sevion
Related Party Transaction [Line Items]
Equity method investment, ownership percentage					3.00%		3.00%
Invested in common shares \| $				$ 500
Warrants to purchase common shares				333,333	500,000		500,000
Neovasc
Related Party Transaction [Line Items]
Equity method investment, ownership percentage					4.00%		4.00%
Warrants to purchase common shares					1,000,000		1,000,000
MabVax
Related Party Transaction [Line Items]
Available-for-sale investment, ownership percentage					1.00%		1.00%
Invested in common shares \| $			$ 400
Investment owned (in shares)			340,909
Warrants to purchase common shares			170,454		1,800,000		1,800,000
Stock price per share (in dollars per share) \| $ / shares			$ 1.10
COCP
Related Party Transaction [Line Items]
Equity method investment, ownership percentage					8.00%		8.00%
Warrants to purchase common shares					1,000,000		1,000,000
ARNO
Related Party Transaction [Line Items]
Available-for-sale investment, ownership percentage					4.00%		4.00%
Warrants to purchase common shares					800,000		800,000
Additional investment \| $	$ 300
InCellDx, Inc
Related Party Transaction [Line Items]
Equity method investment, ownership percentage					27.00%		27.00%
Warrants to purchase common shares					700,000		700,000
Equity Method Investee \| Zebra
Related Party Transaction [Line Items]
Equity method investment, ownership percentage					29.00%		29.00%
Equity Method Investee \| Sevion
Related Party Transaction [Line Items]
Equity method investment, ownership percentage					3.00%		3.00%
Equity Method Investee \| Neovasc
Related Party Transaction [Line Items]
Equity method investment, ownership percentage					4.00%		4.00%
Investee \| ChromaDex Corporation
Related Party Transaction [Line Items]
Available-for-sale investment, ownership percentage					2.00%		2.00%
Investee \| ARNO
Related Party Transaction [Line Items]
Available-for-sale investment, ownership percentage					4.00%		4.00%
Frost Real Estate Holdings LLC
Related Party Transaction [Line Items]
Area of real estate property (in square feet) \| ft²											25
Lease payments per month in first year \| $											$ 66
Lease payments per month in fifth year \| $											75
Rent reduction \| $											$ 200
Reimbursement Of Travel Expense \| Dr Frost
Related Party Transaction [Line Items]
Reimbursement paid to related party for travel \| $					$ 62	$ 167	$ 119	$ 293
Series C Preferred Stock \| Sevion
Related Party Transaction [Line Items]
Investment owned (in shares)				66,667
Common Stock
Related Party Transaction [Line Items]
Stock price per share (in dollars per share) \| $ / shares					$ 9.34		$ 9.34		$ 12.38	$ 13.88
Common Stock \| Sevion
Related Party Transaction [Line Items]
Investment owned (in shares)				666,667
Common Stock \| ARNO
Related Party Transaction [Line Items]
Investment owned (in shares)	714,285
Series A-2 Preferred Stock \| Zebra
Related Party Transaction [Line Items]
Investment owned (in shares)		420,000