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Debt - Narrative (Details)
1 Months Ended 6 Months Ended
Aug. 30, 2013
USD ($)
conversion_right
shares
Jan. 31, 2013
USD ($)
$ / shares
May. 31, 2015
USD ($)
shares
Jun. 30, 2014
USD ($)
shares
Jan. 31, 2013
USD ($)
$ / shares
Jun. 30, 2015
USD ($)
d
institution
conversion_right
$ / shares
shares
Jun. 30, 2014
USD ($)
Dec. 31, 2014
USD ($)
institution
Debt Instrument [Line Items]                
Interest paid           $ 1,724,000 $ 2,771,000  
Gains (losses) on extinguishment of debt           (291,000) $ 2,668,000  
Gain (loss) on embedded derivative           $ 68,000,000    
Number of financial institutions | institution           8   12
OPKO Health Europe                
Debt Instrument [Line Items]                
Long-term Debt           $ 3,225,000   $ 3,043,000
Weighted average interest rate           3.20%   3.40%
Minimum | OPKO Health Europe                
Debt Instrument [Line Items]                
Variable interest rates           2.70%    
Maximum | OPKO Health Europe                
Debt Instrument [Line Items]                
Variable interest rates           6.30%    
Notes                
Debt Instrument [Line Items]                
Convertible notes, conversion           $ 41,442,000    
Long-term Debt           $ 109,203,000   $ 131,454,000
Notes | Notes Due February 1, 2033                
Debt Instrument [Line Items]                
Debt face amount   $ 175,000,000.0     $ 175,000,000.0      
Interest rate of notes payable   3.00%     3.00% 3.00%    
Equivalent redemption price   100.00%     100.00%      
Conversion Rate 141.4827 141.48       141.4827    
Conversion Price | $ / shares   $ 7.07     $ 7.07 $ 7.07    
Number of trading days | d           20    
Convertible debt, threshold percentage of stock price trigger         130.00% 130.00%    
Number of consecutive trading days applicable conversion price           30 days    
Conversion right triggered | conversion_right 1         1    
Convertible notes, conversion $ 16,900,000     $ 70,400,000   $ 36,400,000    
Convertible debt, stock issued from conversion | shares 2,396,145   726,036          
Interest paid       $ 800,000   200,000    
Gains (losses) on extinguishment of debt     $ 30,000     $ (300,000)    
Converted amount     $ 5,000,000          
Common stock trigger price | $ / shares           $ 9.19    
Long-term Debt           $ 46,200,000    
Notes | Notes Due February 1, 2033 | Minimum                
Debt Instrument [Line Items]                
Number of trading days applicable conversion price         20 days      
Notes | Notes Due February 1, 2033 | Maximum                
Debt Instrument [Line Items]                
Number of consecutive trading days applicable conversion price         30 days      
Notes | Notes Due February 1, 2033 | On or after February 1, 2017 and before February 1, 2019                
Debt Instrument [Line Items]                
Equivalent redemption price         100.00%      
Line of Credit                
Debt Instrument [Line Items]                
Weighted average interest rate           5.70%   6.10%
Common stock investments, available for sale | Notes | Notes Due February 1, 2033                
Debt Instrument [Line Items]                
Convertible debt, stock issued from conversion | shares       10,974,431   5,363,896