Fair Value Measurements - Assets And Liabilities Measured At Fair Value (Details) (Fair Value, Measurements, Recurring [Member], USD $) In Thousands, unless otherwise specified	Mar. 31, 2015	Dec. 31, 2014
Assets:
Total assets	$ 70,704	$ 83,394
Liabilities:
Total liabilities	144,298	137,514
Level 1
Assets:
Total assets	60,967	77,044
Level 2
Assets:
Total assets	9,737	6,350
Liabilities:
Total liabilities	0
Level 3
Assets:
Total assets		0
Liabilities:
Total liabilities	144,298	137,514
Embedded conversion option
Liabilities:
Total liabilities	67,787	65,947
Embedded conversion option | Level 3
Liabilities:
Total liabilities	67,787	65,947
Contingent consideration | CURNA
Liabilities:
Total liabilities	457	440
Contingent consideration | CURNA | Level 3
Liabilities:
Total liabilities	457	440
Contingent consideration | OPKO Diagnostics
Liabilities:
Total liabilities	14,402	13,578
Contingent consideration | OPKO Diagnostics | Level 3
Liabilities:
Total liabilities	14,402	13,578
Contingent consideration | OPKO Renal
Liabilities:
Total liabilities	59,410	55,780
Contingent consideration | OPKO Renal | Level 3
Liabilities:
Total liabilities	59,410	55,780
Contingent consideration | OPKO Health Europe
Liabilities:
Total liabilities	2,242	1,769
Contingent consideration | OPKO Health Europe | Level 3
Liabilities:
Total liabilities	2,242	1,769
Money market funds
Assets:
Total assets	56,468	71,286
Money market funds | Level 1
Assets:
Total assets	56,468	71,286
Common stock investments, available for sale
Assets:
Total assets	4,499	5,758
Common stock investments, available for sale | Level 1
Assets:
Total assets	4,499	5,758
Common stock options/warrants
Assets:
Total assets	9,723	6,314
Common stock options/warrants | Level 2
Assets:
Total assets	9,723	6,314
Forward Contracts
Assets:
Total assets	14	36
Forward Contracts | Level 2
Assets:
Total assets	$ 14	$ 36