Fair Value Measurements - Assets And Liabilities Measured At Fair Value (Details) (Fair Value, Measurements, Recurring [Member], USD $) In Thousands, unless otherwise specified	Sep. 30, 2014	Dec. 31, 2013
Level 1
Assets:
Total assets	$ 105,282	$ 174,492
Level 2
Assets:
Total assets	5,782	13,015
Liabilities:
Total liabilities	0
Level 3
Assets:
Total assets		0
Liabilities:
Total liabilities	121,677	178,160
Estimate of Fair Value Measurement
Assets:
Total assets	111,064	187,507
Liabilities:
Total liabilities	121,677	178,160
Embedded conversion option | Level 3
Liabilities:
Total liabilities	50,443	101,087
Embedded conversion option | Estimate of Fair Value Measurement
Liabilities:
Total liabilities	50,443	101,087
Deferred acquisition payments, net of discount | Level 3
Liabilities:
Total liabilities		5,465
Deferred acquisition payments, net of discount | Estimate of Fair Value Measurement
Liabilities:
Total liabilities		5,465
Contingent consideration | CURNA | Level 3
Liabilities:
Total liabilities	423	573
Contingent consideration | CURNA | Estimate of Fair Value Measurement
Liabilities:
Total liabilities	423	573
Contingent consideration | OPKO Diagnostics | Level 3
Liabilities:
Total liabilities	14,493	13,776
Contingent consideration | OPKO Diagnostics | Estimate of Fair Value Measurement
Liabilities:
Total liabilities	14,493	13,776
Contingent consideration | FineTech | Level 3
Liabilities:
Total liabilities		3,124
Contingent consideration | FineTech | Estimate of Fair Value Measurement
Liabilities:
Total liabilities		3,124
Contingent consideration | OPKO Renal | Level 3
Liabilities:
Total liabilities	54,720	53,092
Contingent consideration | OPKO Renal | Estimate of Fair Value Measurement
Liabilities:
Total liabilities	54,720	53,092
Contingent consideration | OPKO Health Europe | Level 3
Liabilities:
Total liabilities	1,598	1,043
Contingent consideration | OPKO Health Europe | Estimate of Fair Value Measurement
Liabilities:
Total liabilities	1,598	1,043
Money market funds | Level 1
Assets:
Total assets	97,694	168,418
Money market funds | Estimate of Fair Value Measurement
Assets:
Total assets	97,694	168,418
Certificates of deposit | Level 2
Assets:
Total assets	0	827
Certificates of deposit | Estimate of Fair Value Measurement
Assets:
Total assets	0	827
Notes Receivabe | Level 2
Assets:
Total assets		6,151
Notes Receivabe | Estimate of Fair Value Measurement
Assets:
Total assets		6,151
Common stock investments, available for sale | Level 1
Assets:
Total assets	7,588	6,074
Common stock investments, available for sale | Estimate of Fair Value Measurement
Assets:
Total assets	7,588	6,074
Common stock options/warrants | Level 2
Assets:
Total assets	5,703	5,988
Common stock options/warrants | Estimate of Fair Value Measurement
Assets:
Total assets	5,703	5,988
Forward Contracts | Level 2
Assets:
Total assets	79	49
Forward Contracts | Estimate of Fair Value Measurement
Assets:
Total assets	$ 79	$ 49