Fair Value Measurements - Assets And Liabilities Measured At Fair Value (Details) (Fair Value, Measurements, Recurring [Member], USD $) In Thousands, unless otherwise specified	Mar. 31, 2014	Dec. 31, 2013
Level 1 [Member]
Assets:
Total assets	$ 137,548	$ 174,492
Level 2 [Member]
Assets:
Total assets	7,614	13,015
Level 3 [Member]
Assets:
Total assets		0
Liabilities:
Total liabilities	184,055	178,160
Estimate of Fair Value Measurement [Member]
Assets:
Total assets	145,162	187,507
Liabilities:
Total liabilities	184,055	178,160
OPKO Spain [Member] | Level 3 [Member]
Liabilities:
Total liabilities		1,043
OPKO Spain [Member] | Estimate of Fair Value Measurement [Member]
Liabilities:
Total liabilities		1,043
Embedded conversion option [Member] | Level 3 [Member]
Liabilities:
Total liabilities	112,199	101,087
Embedded conversion option [Member] | Estimate of Fair Value Measurement [Member]
Liabilities:
Total liabilities	112,199	101,087
Deferred acquisition payments, net of discount [Member] | Level 3 [Member]
Liabilities:
Total liabilities	840	5,465
Deferred acquisition payments, net of discount [Member] | Estimate of Fair Value Measurement [Member]
Liabilities:
Total liabilities	840	5,465
Contingent consideration [Member] | CURNA [Member] | Level 3 [Member]
Liabilities:
Total liabilities	583	573
Contingent consideration [Member] | CURNA [Member] | Estimate of Fair Value Measurement [Member]
Liabilities:
Total liabilities	583	573
Contingent consideration [Member] | Opko Diagnostics [Member] | Level 3 [Member]
Liabilities:
Total liabilities	14,193	13,776
Contingent consideration [Member] | Opko Diagnostics [Member] | Estimate of Fair Value Measurement [Member]
Liabilities:
Total liabilities	14,193	13,776
Contingent consideration [Member] | FineTech [Member] | Level 3 [Member]
Liabilities:
Total liabilities		3,124
Contingent consideration [Member] | FineTech [Member] | Estimate of Fair Value Measurement [Member]
Liabilities:
Total liabilities		3,124
Contingent consideration [Member] | OPKO Renal [Member] | Level 3 [Member]
Liabilities:
Total liabilities	54,819	53,092
Contingent consideration [Member] | OPKO Renal [Member] | Estimate of Fair Value Measurement [Member]
Liabilities:
Total liabilities	54,819	53,092
Contingent consideration [Member] | OPKO Spain [Member] | Level 3 [Member]
Liabilities:
Total liabilities	1,421
Contingent consideration [Member] | OPKO Spain [Member] | Estimate of Fair Value Measurement [Member]
Liabilities:
Total liabilities	1,421
Money market funds [Member] | Level 1 [Member]
Assets:
Total assets	132,343	168,418
Money market funds [Member] | Estimate of Fair Value Measurement [Member]
Assets:
Total assets	132,343	168,418
Certificates of Deposit [Member] | Level 2 [Member]
Assets:
Total assets		827
Certificates of Deposit [Member] | Estimate of Fair Value Measurement [Member]
Assets:
Total assets		827
Notes Receivable [Member] | Level 2 [Member]
Assets:
Total assets		6,151
Notes Receivable [Member] | Estimate of Fair Value Measurement [Member]
Assets:
Total assets		6,151
Common Stock [Member] | Level 1 [Member]
Assets:
Total assets	5,205	6,074
Common Stock [Member] | Estimate of Fair Value Measurement [Member]
Assets:
Total assets	5,205	6,074
Common stock options/warrants [Member] | Level 2 [Member]
Assets:
Total assets	6,797	5,988
Common stock options/warrants [Member] | Estimate of Fair Value Measurement [Member]
Assets:
Total assets	6,797	5,988
Forward Contracts [Member] | Level 2 [Member]
Assets:
Total assets	1	49
Forward Contracts [Member] | Estimate of Fair Value Measurement [Member]
Assets:
Total assets	$ 1	$ 49