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Acquisitions, Investments, and Licenses - Summary of Investments (Details) (USD $)
In Thousands, except Per Share data, unless otherwise specified
Mar. 31, 2014
Dec. 31, 2013
Investment [Line Items]    
Investment, available for sale $ 4,745 $ 4,301
Plus unrealized gains on investments, options and warrants, net 13,120  
Less accumulated losses in investees (20,492)  
Investments, net 35,697 [1] 30,653 [1]
Neovasc [Member]
   
Investment [Line Items]    
Ownership at March 31, 2014 6.00%  
Investment, equity method 3,798  
Underlying equity in net assets 1,558  
Fabrus [Member]
   
Investment [Line Items]    
Ownership at March 31, 2014 12.00%  
Investment, equity method 750  
Underlying equity in net assets (362)  
RXi [Member]
   
Investment [Line Items]    
Ownership at March 31, 2014 17.00%  
Investment, equity method 15,000  
Underlying equity in net assets 1,841  
Pharmasynthez [Member]
   
Investment [Line Items]    
Ownership at March 31, 2014 17.00%  
Investment, equity method 11,300  
Underlying equity in net assets 6,405  
Zebra [Member]
   
Investment [Line Items]    
Ownership at March 31, 2014 19.00%  
Investment, equity method 2,000  
Underlying equity in net assets 840  
Cocrystal/BZNE [Member]
   
Investment [Line Items]    
Ownership at March 31, 2014 16.00%  
Investment, equity method 5,476  
Underlying equity in net assets 20  
Neovasc Options [Member]
   
Investment [Line Items]    
Investment, available for sale 925  
Closing share price at March 31, 2014 for investments available for sale $ 4.10  
ChromaDex [Member]
   
Investment [Line Items]    
Ownership at March 31, 2014 1.00%  
Investment, available for sale 1,320  
Closing share price at March 31, 2014 for investments available for sale $ 1.83  
ARNO [Member]
   
Investment [Line Items]    
Ownership at March 31, 2014 5.00%  
Investment, available for sale 2,000  
Closing share price at March 31, 2014 for investments available for sale $ 2.22  
Cocrystal Warrants [Member]
   
Investment [Line Items]    
Investment, available for sale $ 500  
[1] As of March 31, 2014 and December 31, 2013, total assets include $6.8 million and $6.7 million, respectively, and total liabilities include $11.4 million and $10.4 million, respectively, related to SciVac Ltd (“SciVac”), previously known as SciGen (I.L.) Ltd, a consolidated variable interest entity. SciVac’s consolidated assets are owned by SciVac and SciVac’s consolidated liabilities have no recourse against us. Refer to Note 5.