Composition of Certain Financial Statement Captions (Details) (USD $) In Thousands, unless otherwise specified	Sep. 30, 2013		Dec. 31, 2012
Accounts receivable, net:
Accounts receivable	$ 22,506		$ 21,636
Less: allowance for doubtful accounts	(1,134)		(474)
Accounts receivable, net	21,372	[1]	21,162	[1]
Inventories, net:
Finished products	14,775		17,963
Work in-process	1,450		688
Raw materials	4,426		4,923
Less: inventory reserve	(1,135)		(1,313)
Inventory, net	19,516	[1]	22,261	[1]
Prepaid expense and other assets:
Prepaid supplies	839		443
Prepaid insurance	843		301
Pharmsynthez Note Receivable and Purchase Option	6,755		0
Other receivables	3,818		886
Taxes recoverable	2,992		1,493
Other	4,304		4,750
Prepaid expenses and other current assets	19,551	[1]	7,873	[1]
Intangible assets, net:
Less: accumulated amortization	21,904		14,072
Intangible assets, net	77,333	[1]	84,238	[1]
Accrued expenses:
Taxes payable	3,225		1,614
Deferred revenue	7,040		1,518
Clinical trials	3,543		50
Professional fees	7,203		675
Employee benefits	6,416		3,319
Deferred acquisition payments, net of discount	5,335		6,172
Contingent consideration	3,695		5,126
Interest payable related to the Notes	925		0
Other	5,887		6,182
Accrued expenses	43,269	[1]	24,656	[1]
Other long-term liabilities:
Deferred acquisition payments, net of discount	0		3,931
Mortgages and other debts payable	3,350		5,150
Deferred tax liabilities	164,892		9,777
Other, including deferred revenue	1,006		380
Other long-term liabilities	234,762	[1]	34,168	[1]
Cytochroma [Member]
Other long-term liabilities:
Contingent consideration	51,447		0
Farmadiet [Member]
Other long-term liabilities:
Contingent consideration	542		532
OPKO Diagnostics [Member]
Other long-term liabilities:
Contingent consideration	12,976		11,310
FineTech [Member]
Other long-term liabilities:
Contingent consideration	0		2,578
CURNA [Member]
Other long-term liabilities:
Contingent consideration	549		510
Technologies [Member]
Intangible assets, net:
Intangible assets	52,947		52,810
Customer relationships [Member]
Intangible assets, net:
Intangible assets	22,883		23,088
Product registrations [Member]
Intangible assets, net:
Intangible assets	9,861		9,637
Tradenames [Member]
Intangible assets, net:
Intangible assets	3,702		3,746
Covenants not to compete [Member]
Intangible assets, net:
Intangible assets	8,667		8,662
Other [Member]
Intangible assets, net:
Intangible assets	$ 1,177		$ 367

[1] As of September 30, 2013 and December 31, 2012, total assets include $5.9 million and $5.6 million, respectively, and total liabilities include $8.7 million and $5.5 million, respectively related to SciVac Ltd ("SciVac"), previously known as SciGen (I.L.) Ltd, a consolidated variable interest entity. SciVac’s consolidated assets are owned by SciVac and SciVac’s consolidated liabilities have no recourse against us. Refer to Note 5.