<SEC-DOCUMENT>0000932471-19-005667-index.html : 20190211
<SEC-HEADER>0000932471-19-005667.hdr.sgml : 20190211
<ACCEPTANCE-DATETIME>20190211162354
ACCESSION NUMBER:		0000932471-19-005667
CONFORMED SUBMISSION TYPE:	SC 13G
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20190211
DATE AS OF CHANGE:		20190211

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Opko Health, Inc.
		CENTRAL INDEX KEY:			0000944809
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				752402409
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-51671
		FILM NUMBER:		19585790

	BUSINESS ADDRESS:	
		STREET 1:		4400 BISCAYNE BLVD.
		CITY:			MIAMI
		STATE:			FL
		ZIP:			33137
		BUSINESS PHONE:		305-575-4138

	MAIL ADDRESS:	
		STREET 1:		4400 BISCAYNE BLVD.
		CITY:			MIAMI
		STATE:			FL
		ZIP:			33137

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	eXegenics Inc
		DATE OF NAME CHANGE:	20040505

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	EXEGENICS INC
		DATE OF NAME CHANGE:	20011114

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CYTOCLONAL PHARMACEUTICS INC /DE
		DATE OF NAME CHANGE:	19950503

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			VANGUARD GROUP INC
		CENTRAL INDEX KEY:			0000102909
		IRS NUMBER:				231945930
		STATE OF INCORPORATION:			PA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G

	BUSINESS ADDRESS:	
		STREET 1:		PO BOX 2600
		STREET 2:		V26
		CITY:			VALLEY FORGE
		STATE:			PA
		ZIP:			19482-2600
		BUSINESS PHONE:		6106691000

	MAIL ADDRESS:	
		STREET 1:		PO BOX 2600
		STREET 2:		V26
		CITY:			VALLEY FORGE
		STATE:			PA
		ZIP:			19482-2600
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G
<SEQUENCE>1
<FILENAME>opkohealthinc.htm
<TEXT>
Document 1 - file: opkohealthinc.htm

</DOCUMENT>
</SEC-DOCUMENT>