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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 SPVkUG7h76PuzgJoukg+fylKHzIhzOBRDd/ZoyoEJjff9Hq1p4ogNPjxN29t/X22
 B9vpek/dVOJse7eME3k0RA==

<SEC-DOCUMENT>0001005477-07-001942.txt : 20070315
<SEC-HEADER>0001005477-07-001942.hdr.sgml : 20070315
<ACCEPTANCE-DATETIME>20070315114850
ACCESSION NUMBER:		0001005477-07-001942
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20070313
FILED AS OF DATE:		20070315
DATE AS OF CHANGE:		20070315

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			VION PHARMACEUTICALS INC
		CENTRAL INDEX KEY:			0000944522
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				133671221
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		4 SCIENCE PARK
		CITY:			NEW HAVEN
		STATE:			CT
		ZIP:			06511
		BUSINESS PHONE:		2034984210

	MAIL ADDRESS:	
		STREET 1:		FOUR SCIENCE PARK
		CITY:			NEW HAVEN
		STATE:			CT
		ZIP:			06511

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ONCORX INC
		DATE OF NAME CHANGE:	19950615

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			RAKIN KEVIN
		CENTRAL INDEX KEY:			0001184421

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-26534
		FILM NUMBER:		07695575

	BUSINESS ADDRESS:	
		STREET 1:		GANAISSANCE PHARMACEUTICALS INC
		STREET 2:		5 SCIENCE PARK
		CITY:			NEW HAVEN
		STATE:			CT
		ZIP:			06511
		BUSINESS PHONE:		617-527-9933, X3341

	MAIL ADDRESS:	
		STREET 1:		ONE GATEWAY CENTER, SUITE 702
		CITY:			NEWTON
		STATE:			MA
		ZIP:			02458
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>edgar123.xml
<DESCRIPTION>FORM 4
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2007-03-13</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000944522</issuerCik>
        <issuerName>VION PHARMACEUTICALS INC</issuerName>
        <issuerTradingSymbol>VION</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001184421</rptOwnerCik>
            <rptOwnerName>RAKIN KEVIN</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O VION PHARMACEUTICALS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>4 SCIENCE PARK</rptOwnerStreet2>
            <rptOwnerCity>NEW HAVEN</rptOwnerCity>
            <rptOwnerState>CT</rptOwnerState>
            <rptOwnerZipCode>06511</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2007-03-13</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>15000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>1.59</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>49700</value>
                    <footnoteId id="F1"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">Includes 34,700 restricted shares of common stock granted under the Vion Pharmaceuticals, Inc. 2005 Stock Incentive Plan.  Shares vest at the earlier of: (i) Change of Control, or (ii) in three equal annual installments of 33-1/3% as of each January 15, 2008, January 15, 2009 and January 15, 2010.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>Karen Schmedlin as attorney-in-fact for Kevin Rakin</signatureName>
        <signatureDate>2007-03-15</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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