EX-12.1 5 y00668exv12w1.htm EX-12.1: COMPUTATION OF RATIO OF EARNING TO FIXED CHARGES EX-12.1
Exhibit 12.1
Vion Pharmaceuticals, Inc.
Computation of Ratio of Earnings to Fixed Charges
                                                 
    Nine Months    
    Ended    
    September 30,   Year Ended December 31,
(in thousands except per share data)   2008   2007   2006   2005   2004   2003
Earnings:
                                                
Loss before income taxes
     ($22,942 )     ($34,336 )     ($25,305 )     ($18,001 )     ($16,027 )     ($11,834 )
Add: Fixed charges
     19       22       19       25       22       20  
Less: Capitalized interest
     —       —       —       —       —       —  
     
Earnings
     ($22,937 )     ($34,314 )     ($25,286 )     ($17,976 )     ($16,005 )     ($11,814 )
     
Fixed Charges:
                                                
Estimated interest portion of rent expense
   $ 19     $ 22     $ 19     $ 25     $ 22     $ 20  
Interest expense
     —       —       —       4       —       2  
     
Total Fixed Charges
   $ 19     $ 22     $ 19     $ 29     $ 22     $ 22  
     
Ratio of Earnings to Fixed Charges
     —       —       —       —       —       —  
 
(1)   For purposes of computing this ratio of earnings to fixed charges, fixed charges consist of interest expense and that portion of rental expense deemed to be representative of interest. Earnings consist of loss before income taxes plus fixed charges. Earnings were insufficient to cover fixed charges by $11.8 million in 2003, $16.0 million in 2004, $18.0 million in 2005, $25.3 million in 2006, $34.3 million in 2007 and $22.9 million for the nine months ended September 30, 2008.