Exhibit 99.1

ABN 82 010 975 612

MEETING DOCUMENTATION

2009 ANNUAL GENERAL MEETING

at 3:00pm Monday, 30 November 2009

Terrace Room

Indooroopilly Golf Club

Meiers Road

Indooroopilly QLD 4068

CHAIRMAN’S LETTER

Dear Shareholder

I am pleased to invite you to Progen’s Annual General Meeting (AGM). The meeting is currently scheduled to be held on Monday, 30 November 2009, at the Terrace Room, Indooroopilly Golf Club, Meiers Road, Indooroopilly, QLD, 4068.

As you will be aware, the Company has commenced legal action against several shareholders who the Board allege have contravened the takeovers and substantial shareholdings provisions of the Corporations Act. As one of the central issues in that case is the exercise of voting power at general meetings, the Company has applied to the Supreme Court of Queensland for orders adjourning consideration of the resolutions on the AGM agenda relating to election of directors to a time after that case is determined. The intention is to preserve the status quo on the Board until the case is determined after a trial, which is currently scheduled for February 2010.

The Court will not hear the adjournment order application until 9 November 2009. We will inform shareholders of the outcome and of any effect on the AGM.

The Company has also applied to ASIC for an administrative order extending the time to hold the AGM until late February 2010. If that application is successful, the Board intends to postpone the AGM until 28 February 2010, subject to any orders which may be made by the Court. We will inform shareholders if the AGM is postponed.

Please note that until we further notify you, shareholders should act as if the AGM will proceed on 30 November 2009 at 3.00pm.

At the AGM I will take the opportunity to update shareholders on progress and outlook. I would encourage you to read Progen’s Annual Report for 2009 for information about our objectives and strategies and our achievements and challenges during the past year.

The Annual Report also contains the Company’s Financial Statements (and notes) for the year ended 30 June 2009, the Directors’ Report and the Audit Report. This will be tabled and considered at the AGM.

Subject to any variation or postponement, the AGM will commence at 3.00pm but you will be able to register your attendance from 2.30pm.

If you are unable to attend, I would encourage you to participate by completing and returning the enclosed proxy form in the reply-paid envelope.

I look forward to seeing you at this year’s AGM.

Yours sincerely

Mr Stuart James

Chairman

20 October 2009

DEFINITIONS

The following capitalised terms, which are used in documents forming part of the Meeting Documentation, have the meanings set out below:

‘Annual General Meeting’ means the proposed meeting of all Shareholders currently scheduled for 3.00pm on Monday, 30 November 2009 at the Terrace Room, Indooroopilly Golf Club, Meiers Road, Indooroopilly, QLD 4068 to consider and if thought fit, pass the resolutions set out in the Notice of Annual General Meeting;

‘Associates’ has the meaning given to it by sections 10 to 17 of the Corporations Act;

‘ASIC’ means the Australian Securities and Investments Commission;

‘ASX’ means the Australian Securities Exchange Limited ABN 98 008 624 691;

‘Board’ means the Board of Directors of Progen;

‘Corporations Act’ means the Corporations Act 2001 (Cth);

‘Director’ means a Director of Progen;

‘Explanatory Memorandum’ means the document forming part of the Meeting Documentation containing information on the resolutions set out in the Notice of Annual General Meeting;

‘Listing Rules’ means the Listing Rules of ASX;

‘Meeting Documentation’ means:

· the letter from the Chairman to Shareholders dated 20 October 2009;

· the Explanatory Memorandum;

· the Notice of Annual General Meeting; and

· the proxy form for the Annual General Meeting;

‘Notice of Annual General Meeting’ means the Notice dated 23 October 2009 which is enclosed in the Meeting Documentation;

‘Progen’ or ‘Company’ means Progen Pharmaceuticals Limited ABN 82 010 975 612;

‘Share’ means a fully paid ordinary share issued in the capital of Progen;

‘Shareholder’ means a holder of Shares.

NOTICE OF ANNUAL GENERAL MEETING

Notice is given that the Annual General Meeting of Progen Pharmaceuticals Limited will be held at the Terrace Room, Indooroopilly Golf Club, Meiers Road, Indooroopilly, QLD 4068 on Monday, 30 November 2009 at 3.00pm.

ORDINARY BUSINESS

CHAIRMAN’S ADDRESS AND PRESENTATION

THE FINANCIAL STATEMENTS AND REPORTS

To receive and consider the Directors’ Report, Financial Statements, Directors’ Declaration and Independent Audit Report for the financial year ended 30 June 2009.

ORDINARY RESOLUTIONS

1. DIRECTORS’ REMUNERATION REPORT

To consider and if thought fit, to pass the following resolution in accordance with s250R(2) of the Corporations Act:

“That the section of the Directors Report in the 2009 Annual Report dealing with the remuneration of the Company’s Directors, Company Secretary and Senior Executives described as “Remuneration Report” be adopted.”

NB: This resolution shall be determined as if it were an ordinary (majority) resolution, but under s250R(3) of the Corporations Act, the vote is advisory only and does not bind the Directors of the Company.

2. RE-ELECTION OF DIRECTOR – MR STUART JAMES