Exhibit 23.1

Consent of Independent Registered Public Accounting Firm

The Board of Directors
NeoPharm, Inc.:

We consent to the incorporation by reference in the registration statements (Nos. 333-03725, 333-66365, and 333-104586) on Form S-8 and (No. 333-109340) on Form S-3 of NeoPharm, Inc. of our reports dated March 15, 2006, with respect to the consolidated balance sheets of NeoPharm, Inc. as of December 31, 2005 and 2004, and the related consolidated statements of operations, stockholders’ equity, and cash flows, for each of the years in the three-year period ended December 31, 2005, and related financial statement schedule, management’s assessment of the effectiveness of internal control over financial reporting as of December 31, 2005 and the effectiveness of internal control over financial reporting as of December 31, 2005, which reports appear in the December 31, 2005 annual report on Form 10-K of NeoPharm, Inc.

/s/ KPMG LLP

Chicago, Illinois
March 15, 2006

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