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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 HXomAqOHp2OiC0/D2HlFnT15GYfh46lWxYEV87IH1AHIjJW4fD8MP1sxn/gf7Rzx
 iZw0dePLBCsMa+ufMfiInQ==

<SEC-DOCUMENT>0001104659-05-045905.txt : 20050927
<SEC-HEADER>0001104659-05-045905.hdr.sgml : 20050927
<ACCEPTANCE-DATETIME>20050927123643
ACCESSION NUMBER:		0001104659-05-045905
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20050923
FILED AS OF DATE:		20050927
DATE AS OF CHANGE:		20050927

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			NEOPHARM INC
		CENTRAL INDEX KEY:			0000942788
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				510327886
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0907

	BUSINESS ADDRESS:	
		STREET 1:		150 FIELD DRIVE
		STREET 2:		SUITE 195
		CITY:			LAKE FORREST
		STATE:			IL
		ZIP:			60045
		BUSINESS PHONE:		8472958678

	MAIL ADDRESS:	
		STREET 1:		C/O WILSON SONSIN GOODRICH & ROSETI
		STREET 2:		650 PAGE MILL ROAD
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94304

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Becker Frank C
		CENTRAL INDEX KEY:			0001308776

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-12493
		FILM NUMBER:		051104691

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		847-625-5610

	MAIL ADDRESS:	
		STREET 1:		1800 NATIONS DRIVE SUITE 204
		CITY:			GURNEE
		STATE:			IL
		ZIP:			60031
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>a4.xml
<DESCRIPTION>4
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-09-23</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000942788</issuerCik>
        <issuerName>NEOPHARM INC</issuerName>
        <issuerTradingSymbol>NEOL</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001308776</rptOwnerCik>
            <rptOwnerName>Becker Frank C</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>1800 NATIONS DRIVE, SUITE 204</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>GURNEE</rptOwnerCity>
            <rptOwnerState>IL</rptOwnerState>
            <rptOwnerZipCode>60031</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chairman</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common</value>
            </securityTitle>
            <transactionDate>
                <value>2005-09-23</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>28000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>11.91</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>42613</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <ownerSignature>
        <signatureName>/s/ Lawrence A. Kenyon, by power of attorney</signatureName>
        <signatureDate>2005-09-27</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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