X0303 4 2009-08-04 0 0000939767 EXELIXIS INC EXEL 0001387306 Lamb Peter C/O EXELIXIS, INC. 249 EAST GRAND AVE., PO BOX 511 SOUTH SAN FRANCISCO CA 94083-0511 0 1 0 0 SVP, Discovery Research & CSO Option (right to buy) 7.47 2009-08-04 4 D 0 25000 D 2004-04-15 2013-04-14 Common Stock 25000 0 D Option (right to buy) 5.63 2009-08-05 4 A 0 20000 A 2010-08-05 2015-10-17 Common Stock 20000 20000 D Option (right to buy) 7.85 2009-08-04 4 D 0 10000 D 2003-12-20 2012-12-19 Common Stock 10000 0 D Option (right to buy) 5.63 2009-08-05 4 A 0 8000 A 2010-08-05 2015-10-17 Common Stock 8000 8000 D Option (right to buy) 8.92 2009-08-04 4 D 0 35000 D 2005-12-13 2014-12-12 Common Stock 35000 0 D Option (right to buy) 5.63 2009-08-05 4 A 0 28000 A 2010-08-05 2015-10-17 Common Stock 28000 28000 D Option (right to buy) 9.00 2009-08-04 4 D 0 1750 D 2002-01-15 2011-01-14 Common Stock 1750 0 D Option (right to buy) 5.63 2009-08-05 4 A 0 1400 A 2010-08-05 2015-10-17 Common Stock 1400 1400 D Option (right to buy) 9.00 2009-08-04 4 D 0 80000 D 2008-01-02 2017-01-01 Common Stock 80000 0 D Option (right to buy) 5.63 2009-08-05 4 A 0 39999 A 2010-08-05 2015-10-17 Common Stock 39999 39999 D Option (righ to buy) 5.63 2009-08-05 4 A 0 24001 A 2010-08-05 2015-10-17 Common Stock 24001 24001 D Option (right to buy) 9.42 2009-08-04 4 D 0 120000 D 2007-01-02 2016-01-01 Common Stock 120000 0 D Option (right to buy) 5.63 2009-08-05 4 A 0 84000 A 2010-08-05 2015-10-17 Common Stock 84000 84000 D Option (right to buy) 5.63 2009-08-05 4 A 0 12000 A 2010-08-05 2015-10-17 Common Stock 12000 12000 D Option (right to buy) 9.85 2009-08-04 4 D 0 40000 D 2008-01-19 2017-01-18 Common Stock 40000 0 D Option (right to buy) 5.63 2009-08-05 4 A 0 19333 A 2010-08-05 2015-10-17 Common Stock 19333 19333 D Option (right to buy) 5.63 2009-08-05 4 A 0 12667 A 2010-08-05 2015-10-17 Common Stock 12667 12667 D Option (right to buy) 9.91 2009-08-04 4 D 0 125000 D 2008-12-06 2017-12-05 Common Stock 125000 0 D Option (right to buy) 5.63 2009-08-05 4 A 0 39583 A 2010-08-05 2015-10-17 Common Stock 39583 39583 D Option (right to buy) 5.63 2009-08-05 4 A 0 60417 A 2010-08-05 2015-10-17 Common Stock 60417 60417 D Option (right to buy) 16.62 2009-08-04 4 D 0 10000 D 2003-01-01 2011-12-31 Common Stock 10000 0 D Option (right to buy) 5.63 2009-08-05 4 A 0 2500 A 2010-08-05 2015-10-17 Common Stock 2500 2500 D Option (right to buy) 20.125 2009-08-04 4 D 0 47250 D 2001-10-15 2010-10-31 Common Stock 47250 0 D Option (right to buy) 5.63 2009-08-05 4 A 0 525 A 2010-08-05 2015-10-17 Common Stock 525 525 D The option provided for vesting as follows: twenty five percent (25%) of the shares one year from date of grant, and the remaining shares in 36 equal monthly installments thereafter. On August 4, 2009, the Issuer cancelled, pursuant to the Issuer's option exchange program, an option for 25,000 shares of the Issuer's common stock granted to the reporting person on April 15, 2003. In exchange, on August 5, 2009, the reporting person received a replacement option for 20,000 shares of the Issuer's common stock, having an exercise price of $5.63. Option granted pursuant to Issuer's 2000 Equity Incentive Plan. One hundred percent (100%) of the shares vest one year from date of grant. On August 4, 2009, the Issuer cancelled, pursuant to the Issuer's option exchange program, an option for 10,000 shares of the Issuer's common stock granted to the reporting person on December 20, 2002. In exchange, on August 5, 2009, the reporting person received a replacement option for 8,000 shares of the Issuer's common stock, having an exercise price of $5.63. On August 4, 2009, the Issuer cancelled, pursuant to the Issuer's option exchange program, an option for 35,000 shares of the Issuer's common stock granted to the reporting person on December 13, 2004. In exchange, on August 5, 2009, the reporting person received a replacement option for 28,000 shares of the Issuer's common stock, having an exercise price of $5.63. On August 4, 2009, the Issuer cancelled, pursuant to the Issuer's option exchange program, an option for 1,750 shares of the Issuer's common stock granted to the reporting person on January 15, 2001. In exchange, on August 5, 2009, the reporting person received a replacement option for 1,400 shares of the Issuer's common stock, having an exercise price of $5.63. Option granted pursuant to Issuer's 2000 Equity Incentive Plan. Thirty-three percent (33%) of the shares vest one year from date of grant, and the remaining shares vest in 24 equal monthly installments thereafter. On August 4, 2009, the Issuer cancelled, pursuant to the Issuer's option exchange program, an option for 80,000 shares of the Issuer's common stock granted to the reporting person on January 2, 2007. In exchange, on August 5, 2009, the reporting person received two replacement options for 39,999 and 24,001 shares of the Issuer's common stock, respectively, each having an exercise price of $5.63. On August 4, 2009, the Issuer cancelled, pursuant to the Issuer's option exchange program, an option for 120,000 shares of the Issuer's common stock granted to the reporting person on January 2, 2006. In exchange, on August 5, 2009, the reporting person received two replacement options for 84,000 and 12,000 shares of the Issuer's common stock, respectively, each having an exercise price of $5.63. On August 4, 2009, the Issuer cancelled, pursuant to the Issuer's option exchange program, an option for 40,000 shares of the Issuer's common stock granted to the reporting person on January 19, 2007. In exchange, on August 5, 2009, the reporting person received two replacement options for 19,333 and 12,667 shares of the Issuer's common stock, respectively, each having an exercise price of $5.63. On August 4, 2009, the Issuer cancelled, pursuant to the Issuer's option exchange program, an option for 125,000 shares of the Issuer's common stock granted to the reporting person on December 6, 2007. In exchange, on August 5, 2009, the reporting person received two replacement options for 39,583 and 60,417 shares of the Issuer's common stock, respectively, each having an exercise price of $5.63. On August 4, 2009, the Issuer cancelled, pursuant to the Issuer's option exchange program, an option for 10,000 shares of the Issuer's common stock granted to the reporting person on January 1, 2002. In exchange, on August 5, 2009, the reporting person received a replacement option for 2,500 shares of the Issuer's common stock, having an exercise price of $5.63. On August 4, 2009, the Issuer cancelled, pursuant to the Issuer's option exchange program, an option for 47,250 shares of the Issuer's common stock granted to the reporting person on October 15, 2000. In exchange, on August 5, 2009, the reporting person received a replacement option for 525 shares of the Issuer's common stock, having an exercise price of $5.63. /s/ James B. Bucher, Attorney in Fact 2009-08-06