X0202 4 2007-05-14 0 0000939767 EXELIXIS INC EXEL 0001202102 SCANGOS GEORGE A C/O EXELIXIS INC. 170 HARBOR WAY, PO BOX 0511 SOUTH SAN FRANCISCO CA 94083-0511 1 1 0 0 President & CEO Common Stock 2007-05-14 4 S 0 100 11.60 D 1323531 D Common Stock 2007-05-14 4 S 0 100 11.54 D 1323431 D Common Stock 2007-05-14 4 S 0 100 11.55 D 1323331 D Common Stock 2007-05-14 4 S 0 100 11.37 D 1323231 D Common Stock 2007-05-14 4 S 0 300 11.35 D 1322931 D Common Stock 2007-05-14 4 S 0 100 11.39 D 1322831 D Common Stock 2007-05-14 4 S 0 200 11.36 D 1322631 D Common Stock 2007-05-14 4 S 0 100 11.38 D 1322531 D Common Stock 2007-05-14 4 S 0 100 11.33 D 1322431 D Common Stock 2007-05-14 4 S 0 200 11.29 D 1322231 D Common Stock 2007-05-14 4 S 0 200 11.21 D 1322031 D Common Stock 2007-05-14 4 S 0 100 11.24 D 1321931 D Common Stock 2007-05-14 4 S 0 100 11.25 D 1321831 D Common Stock 2007-05-14 4 S 0 100 11.20 D 1321731 D Common Stock 2007-05-14 4 S 0 300 11.23 D 1321431 D Common Stock 2007-05-14 4 S 0 100 11.27 D 1321331 D Common Stock 2007-05-14 4 S 0 100 11.19 D 1321231 D Common Stock 2007-05-14 4 S 0 100 11.18 D 1321131 D Common Stock 6855 I By Trust Common Stock 6855 I By Trust Common Stock 2945 I By 401(k) Plan The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 15, 2006. Shares held by George A. Scangos and Leslie S. Wilson, as Trustees of the Katherine Scangos Trust. Shares held by George A. Scangos and Leslie S. Wilson, as Trustees of the Jennifer Scangos Trust. Represents units in the Exelixis stock fund based on a plan statement dated March 31, 2007. /s/ George A. Scangos 2007-05-15