CONSOLIDATED STATEMENTS OF INCOME - USD ($) shares in Thousands, $ in Thousands	12 Months Ended
	Jan. 02, 2026	Jan. 03, 2025	Dec. 29, 2023
Revenues:
Total revenues	$ 2,320,126	$ 2,168,701	$ 1,830,208
Operating expenses:
Cost of goods sold	83,697	76,216	72,547
Research and development	825,001	910,408	1,044,071
Selling, general and administrative	518,727	492,128	542,705
Impairment of long-lived assets	0	51,672	0
Restructuring	20,510	33,660	0
Total operating expenses	1,447,935	1,564,084	1,659,323
Income from operations	872,191	604,617	170,885
Interest income	69,213	77,156	86,543
Other income (expenses), net	(198)	(133)	93
Income before income taxes	941,206	681,640	257,521
Provision for income taxes	158,636	160,373	49,756
Net income	$ 782,570	$ 521,267	$ 207,765
Net income
Basic (in dollars per share)	$ 2.88	$ 1.80	$ 0.65
Diluted (in dollars per share)	$ 2.78	$ 1.76	$ 0.65
Weighted-average common shares outstanding:
Basic (in shares)	271,567	290,030	318,151
Diluted (in shares)	281,863	296,132	321,464
Net product revenues
Revenues:
Total revenues	$ 2,122,804	$ 1,809,395	$ 1,628,879
Collaboration services revenues
Revenues:
Total revenues	$ 197,322	$ 359,306	$ 201,329