Collaboration Agreements and Business Development Activities - Ipsen Collaboration Narrative (Details) $ in Millions, $ in Millions	12 Months Ended
	Jan. 02, 2026 USD ($)	Jan. 03, 2025 USD ($)	Jan. 03, 2025 CAD ($)	Dec. 31, 2016 USD ($)	Jan. 02, 2026 CAD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaboration agreement percent of royalty on net sale	3.00%
Collaborative arrangement with Ipsen
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaboration period to achieve specified levels of commercial performance	10 years
Upfront payments				$ 210.0
Milestone payments earned to date	$ 659.2
Milestone payments earned	5.0	$ 164.7
Eligible payment from collaboration for development and regulatory milestone achievement under collaborations agreement	2.0
Maximum amount eligible for commercial milestones under collaborations agreement	$ 200.0				$ 23.5
Collaboration agreement percent of royalty on net sale	3.00%
Research and development arrangement performed for others, reimbursement for costs incurred, percent	35.00%
Revenue from contract with customer, commercial sales milestone		2.2
Revenue from contract with customer, regulatory milestone	$ 5.0	12.5
Cumulative net sales milestone		600.0	$ 30.0
Collaborative arrangement with Ipsen | License revenues
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue from contract with customer, commercial sales milestone	4.3	150.0
Revenue from contract with customer, regulatory milestone upon submission of application		10.8
Collaborative arrangement with Ipsen | Collaboration services revenues
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue from contract with customer, regulatory milestone upon submission of application	$ 0.4	$ 0.6
Collaborative arrangement with Ipsen | Minimum | Final tier
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Percent of royalty on net sale	22.00%
Collaborative arrangement with Ipsen | Maximum | Final tier
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Percent of royalty on net sale	26.00%