Segment Reporting - Segment and Consolidated Net Income (Details) - USD ($) $ in Thousands	12 Months Ended
	Jan. 02, 2026	Jan. 03, 2025	Dec. 29, 2023
Segment Reporting Information [Line Items]
Revenues	$ 2,320,126	$ 2,168,701	$ 1,830,208
Less:
Cost of goods sold	83,697	76,216	72,547
Interest income	(69,213)	(77,156)	(86,543)
Provision for income taxes	158,636	160,373	49,756
Net income	782,570	521,267	207,765
Reportable Segment
Segment Reporting Information [Line Items]
Revenues	2,320,126	2,168,701	1,830,208
Less:
Cost of goods sold	83,697	76,216	72,547
Drug discovery	89,931	94,842	215,085
Development	567,843	665,847	669,240
Selling, general and administrative	446,536	428,962	470,680
Other segment items	260,126	298,350	231,678
Interest income	(69,213)	(77,156)	(86,543)
Provision for income taxes	158,636	160,373	49,756
Net income	$ 782,570	$ 521,267	$ 207,765