<SEC-DOCUMENT>0000936402-18-000081-index.html : 20181004
<SEC-HEADER>0000936402-18-000081.hdr.sgml : 20181004
<ACCEPTANCE-DATETIME>20181004164343
ACCESSION NUMBER:		0000936402-18-000081
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		14
CONFORMED PERIOD OF REPORT:	20181004
ITEM INFORMATION:		Other Events
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20181004
DATE AS OF CHANGE:		20181004

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Shire plc
		CENTRAL INDEX KEY:			0000936402
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37896
		FILM NUMBER:		181108275

	BUSINESS ADDRESS:	
		STREET 1:		BLOCK 2, MIESIAN PLAZA
		STREET 2:		50-58 BAGGOT STREET LOWER
		CITY:			DUBLIN 2
		STATE:			L2
		ZIP:			D02 HW68
		BUSINESS PHONE:		353-1-609-6000

	MAIL ADDRESS:	
		STREET 1:		BLOCK 2, MIESIAN PLAZA
		STREET 2:		50-58 BAGGOT STREET LOWER
		CITY:			DUBLIN 2
		STATE:			L2
		ZIP:			D02 HW68

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Shire Ltd.
		DATE OF NAME CHANGE:	20080523

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Shire plc
		DATE OF NAME CHANGE:	20051125

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	SHIRE PHARMACEUTICALS GROUP PLC
		DATE OF NAME CHANGE:	19980302
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>a8-kxoctober42018file.htm
<DESCRIPTION>8-K
<TEXT>
Document 1 - file: a8-kxoctober42018file.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>oct12018-form8ddxe991.htm
<DESCRIPTION>EXHIBIT 99.1
<TEXT>
Document 2 - file: oct12018-form8ddxe991.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.2
<SEQUENCE>3
<FILENAME>oct12018-form8ddxe992.htm
<DESCRIPTION>EXHIBIT 99.2
<TEXT>
Document 3 - file: oct12018-form8ddxe992.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.3
<SEQUENCE>4
<FILENAME>oct12018-form8ddxe993.htm
<DESCRIPTION>EXHIBIT 99.3
<TEXT>
Document 4 - file: oct12018-form8ddxe993.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.4
<SEQUENCE>5
<FILENAME>oct12018-form8ddxe994.htm
<DESCRIPTION>EXHIBIT 99.4
<TEXT>
Document 5 - file: oct12018-form8ddxe994.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.5
<SEQUENCE>6
<FILENAME>oct12018-form8ddxe995.htm
<DESCRIPTION>EXHIBIT 99.5
<TEXT>
Document 6 - file: oct12018-form8ddxe995.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.6
<SEQUENCE>7
<FILENAME>oct12018-form8ddxe996.htm
<DESCRIPTION>EXHIBIT 99.6
<TEXT>
Document 7 - file: oct12018-form8ddxe996.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.7
<SEQUENCE>8
<FILENAME>oct12018-form8ddxe997.htm
<DESCRIPTION>EXHIBIT 99.7
<TEXT>
Document 8 - file: oct12018-form8ddxe997.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.8
<SEQUENCE>9
<FILENAME>oct12018-form8ddxe998.htm
<DESCRIPTION>EXHIBIT 99.8
<TEXT>
Document 9 - file: oct12018-form8ddxe998.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.9
<SEQUENCE>10
<FILENAME>october22018-rule29xexhibi.htm
<DESCRIPTION>EXHIBIT 99.9
<TEXT>
Document 10 - file: october22018-rule29xexhibi.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.10
<SEQUENCE>11
<FILENAME>october22018-pdmrxexhibit9.htm
<DESCRIPTION>EXHIBIT 99.10
<TEXT>
Document 11 - file: october22018-pdmrxexhibit9.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.11
<SEQUENCE>12
<FILENAME>october32018-rule29xexhibi.htm
<DESCRIPTION>EXHIBIT 99.11
<TEXT>
Document 12 - file: october32018-rule29xexhibi.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.12
<SEQUENCE>13
<FILENAME>october42018-rule29xexhibi.htm
<DESCRIPTION>EXHIBIT 99.12
<TEXT>
Document 13 - file: october42018-rule29xexhibi.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>14
<FILENAME>shirelogobluergba60.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 14 - file: shirelogobluergba60.jpg

</DOCUMENT>
</SEC-DOCUMENT>