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Segment Reporting (Segment Revenue and Contribution) (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Segment Reporting Information [Line Items]    
Revenues $ 3,765.7 $ 3,572.3
Contribution margin 2,136.5 2,132.3
Unallocated corporate and shared functional costs, including G&A expenses 529.5 555.9
Expense related to the unwind of inventory fair value adjustments 33.5 480.4
One-time employee related costs 0.0 (4.0)
Costs relating to license arrangements 10.0 0.0
Amortization of acquired intangible assets 484.0 364.0
Integration and acquisition costs 239.7 116.0
Reorganization costs 5.3 5.5
Gain on sale of product rights 0.0 (5.5)
Depreciation 140.2 122.9
Operating income from continuing operations $ 694.3 $ 497.1
Operating margin percentage 18.40% 13.90%
Other expense, net $ (101.2) $ (134.7)
Income from continuing operations before income taxes and equity in earnings/(losses) of equity method investees 593.1 362.4
Rare Disease    
Segment Reporting Information [Line Items]    
Revenues 2,828.3 2,603.3
Contribution margin 1,366.6 1,339.7
Neuroscience    
Segment Reporting Information [Line Items]    
Revenues 937.4 969.0
Contribution margin $ 769.9 $ 792.6