Consolidated Statements of Operations - USD ($) shares in Millions, $ in Millions	3 Months Ended
	Mar. 31, 2018	Mar. 31, 2017
Revenues:
Product sales	$ 3,637.1	$ 3,412.3
Royalties and other revenues	128.6	160.0
Total revenues	3,765.7	3,572.3
Costs and expenses:
Cost of sales	1,132.4	1,327.0
Research and development	405.2	379.3
Selling, general and administrative	804.8	888.9
Amortization of acquired intangible assets	484.0	364.0
Integration and acquisition costs	239.7	116.0
Reorganization costs	5.3	5.5
Gain on sale of product rights	0.0	(5.5)
Total operating expenses	3,071.4	3,075.2
Operating income from continuing operations	694.3	497.1
Interest income	2.6	3.1
Interest expense	(127.0)	(142.3)
Other income, net	23.2	4.5
Total other expense, net	(101.2)	(134.7)
Income from continuing operations before income taxes and equity in earnings/(losses) of equity method investees	593.1	362.4
Income taxes	(43.3)	(6.8)
Equity in earnings/(losses) of equity method investees, net of taxes	0.8	(0.8)
Income from continuing operations, net of taxes	550.6	354.8
Gain from discontinued operations, net of taxes	0.0	20.2
Net income	$ 550.6	$ 375.0
Earnings per Ordinary Share – basic
Earnings from continuing operations (in usd per share)	$ 0.61	$ 0.39
Earnings from discontinued operations (in usd per share)	0.00	0.02
Earnings per Ordinary Share - basic (in usd per share)	0.61	0.41
Earnings per Ordinary Share – diluted
Earnings from continuing operations (in usd per share)	0.60	0.39
Earnings from discontinued operations (in usd per share)	0.00	0.02
Earnings per Ordinary Share - diluted (in usd per share)	$ 0.60	$ 0.41
Weighted average number of shares:
Basic (in shares)	909.5	904.1
Diluted (in shares)	912.1	911.8