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Business Combinations (Acquisition of Baxalta) (Narrative) (Details)
$ / shares in Units, shares in Millions, $ in Millions
3 Months Ended 9 Months Ended
Jun. 03, 2016
USD ($)
$ / shares
shares
Sep. 30, 2017
USD ($)
Sep. 30, 2016
USD ($)
Sep. 30, 2017
USD ($)
Sep. 30, 2016
USD ($)
Dec. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
Business Acquisition [Line Items]              
Goodwill   $ 19,718.4 $ 14,850.6 $ 19,718.4 $ 14,850.6 $ 17,888.2 $ 4,147.8
Integration and acquisition costs   237.0 $ 284.5 696.7 $ 738.6    
Baxalta              
Business Acquisition [Line Items]              
Purchase price paid per share of acquiree, in cash (in USD per share) | $ / shares $ 18.00            
Shares issued for acquisition (in shares) | shares 305.2            
Cost of sales adjustment       85.2      
Amortization adjustment       23.3      
Goodwill $ 12,498.6 12,498.6   12,498.6      
Maximum amount of contingent cash consideration 1,500.0            
Contingent consideration payable 165.0            
Defined benefit net liability 610.4            
Fair value of plan assets 358.5            
Integration and acquisition costs   238.1   548.6      
Baxalta | Currently marketed products              
Business Acquisition [Line Items]              
Intangible assets $ 21,165.0 21,165.0   21,165.0      
Weighted average amortization period of acquired amortizable intangible assets 21 years            
Baxalta | In-Process Research and Development (IPR&D)              
Business Acquisition [Line Items]              
Intangible assets $ 160.0 $ 160.0   $ 160.0      
Discount rate used in determining fair value of acquired in process research and development, low rate 9.50%            
Baxalta | Minimum | Currently marketed products              
Business Acquisition [Line Items]              
Estimated useful life of intangible assets 6 years            
Baxalta | Maximum | Currently marketed products              
Business Acquisition [Line Items]              
Estimated useful life of intangible assets 23 years            
Baxalta | ADS              
Business Acquisition [Line Items]              
Shire shares per Baxalta share 0.1482            
Baxalta | Common stock              
Business Acquisition [Line Items]              
Shire shares per Baxalta share 0.4446