Consolidated Statements of Operations - USD ($) shares in Millions, $ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2017	Jun. 30, 2016	Jun. 30, 2017	Jun. 30, 2016
Revenues:
Product sales	$ 3,591.8	$ 2,322.1	$ 7,004.1	$ 3,949.4
Royalties and other revenues	154.0	107.0	314.0	189.0
Total revenues	3,745.8	2,429.1	7,318.1	4,138.4
Costs and expenses:
Cost of sales	1,108.9	778.1	2,435.9	1,026.7
Research and development	542.4	294.8	921.7	511.9
Selling, general and administrative	899.1	675.3	1,788.0	1,150.2
Amortization of acquired intangible assets	434.1	213.0	798.1	347.6
Integration and acquisition costs	343.7	363.0	459.7	454.1
Reorganization costs	13.6	11.0	19.1	14.3
Loss/(gain) on sale of product rights	4.8	(2.3)	(0.7)	(6.5)
Total operating expenses	3,346.6	2,332.9	6,421.8	3,498.3
Operating income from continuing operations	399.2	96.2	896.3	640.1
Interest income	1.1	1.6	4.2	2.6
Interest expense	(141.3)	(87.2)	(283.6)	(131.9)
Other income/(expense), net	2.5	6.0	7.0	(2.5)
Total other expense, net	(137.7)	(79.6)	(272.4)	(131.8)
Income from continuing operations before income taxes and equity in earnings/(losses) of equity method investees	261.5	16.6	623.9	508.3
Income taxes	(24.3)	70.9	(31.1)	(11.2)
Equity in earnings/(losses) of equity method investees, net of taxes	4.3	(0.9)	3.5	(1.0)
Income from continuing operations, net of taxes	241.5	86.6	596.3	496.1
(Loss)/gain from discontinued operations, net of taxes	(1.2)	(248.7)	19.0	(239.2)
Net income/(loss)	$ 240.3	$ (162.1)	$ 615.3	$ 256.9
Earnings/(loss) per Ordinary Share – basic
Earnings from continuing operations (in usd per share)	$ 0.27	$ 0.12	$ 0.66	$ 0.78
(Loss)/gain from discontinued operations (in usd per share)	0.00	(0.36)	0.02	(0.38)
Earnings/(loss) per Ordinary Share - basic (in usd per share)	0.27	(0.24)	0.68	0.40
Earnings/(loss) per Ordinary Share – diluted
Earnings from continuing operations (in usd per share)	0.26	0.12	0.65	0.77
(Loss)/earnings from discontinued operations (in usd per share)	0.00	(0.36)	0.02	(0.37)
Earnings/(loss) per Ordinary Share - diluted (in usd per share)	$ 0.26	$ (0.24)	$ 0.67	$ 0.40
Weighted average number of shares:
Basic (in shares)	906.4	682.8	905.3	637.3
Diluted (in shares)	912.7	682.8	912.3	640.1