X0306 4 2018-04-06 0 0001098972 AGENUS INC AGEN 0000935679 ARMEN GARO H C/O AGENUS INC., 3 FORBES ROAD LEXINGTON MA 02421 1 1 0 0 Chairman and CEO Common Stock 2018-04-06 4 J 0 140974 4.82 D 1221433 D Common Stock 2018-09-27 4 J 0 300000 2.16 A 1521433 D Common Stock 2018-09-27 4 J 0 225000 2.16 D 1296433 D Common Stock 2019-12-17 4 J 0 66000 3.88 D 1230433 D Common Stock 2019-12-19 4 J 0 195358 3.77 D 1035075 D Common Stock 229046 I Antigenics LLC Represents shares donated to a charitable organization. Represents required distribution from the Garo Armen 2017 2 Year AG GRAT. Represents deposit of Agenus Inc. common stock into the Garo Armen 2018 2 Year AG GRAT. Dr. Armen is trustee and has investment authority for the Garo Armen 2018 2 Year AG GRAT holder of 225,000 shares of Agenus Inc. common stock. Dr. Armen is Chairman of the Board of Managers and a member of Antigenics LLC ("Antigenics") which as of the date of this reports owns 4,046 shares of Agenus Inc. common stock. Dr. Armen has a pecuniary interest in only a portion of the shares held by Antigenics and disclaims beneficial ownership to the extent of his pecuniary interest therein. /s/Evan D. Kearns, as Attorney-in-Fact for Garo H. Armen 2019-12-23