X0303 4 2011-01-18 0 0001098972 AGENUS INC AGEN 0000935679 ARMEN GARO H 162 FIFTH AVENUE SUITE 900 NEW YORK NY 10010 0 1 0 0 Chairman & CEO Common Stock 2011-01-20 4 A 0 253980 0.94 A 2522797 D Common Stock 5475372 I by trusts, Armen Partners and Antigenics Holdings LLC Restricted Stock 2011-01-18 4 A 0 253980 A 2011-01-20 Common Stock 253980 2694430 D Represents settlement of restricted stock granted on January 18, 2011 partly in lieu of an annual cash bonus for 2010 performance. Dr. Armen is trustee and has investment authority for the Garo Armen 2009 2 year GRAT and the Garo Armen 2009 4 year GRAT, each holding 1,607,183 and 2,336,246 shares of Agenus Inc. common stock, respectively. Dr. Armen disclaims beneficial ownership therein. Dr. Armen is the General Partner of Armen Partners LP. As of the date of this report Armen Partners owns a total of 1,507,667 shares of Agenus Inc. common stock. Dr. Armen is also CEO, Chairman of hte Board of Managers and a member of Antigenics Holdings LLC ("Holdings") which as of the date of this report owns 24,276 shares of Agenus In.c common stock. Dr. Armen has a pecuniary interest in only a portion of the shares held by Armen Partners and Holdings, and disclaims beneficial ownership except to the extent of his pecuniary interest therein. Restricted stock granted on January 18, 2011 in accordance with the Agenus Inc. Equity Incentive Plan partly in lieu of an annual cash bonus for 2010 performance. Christine M. Klaskin, by Power of Attorney 2011-01-20