X0306 4 2023-01-05 0 0001098972 AGENUS INC AGEN 0000935679 ARMEN GARO H C/O AGENUS INC. 3 FORBES ROAD LEXINGTON MA 02421 1 1 0 0 Chairman and CEO Common Stock 2023-01-05 4 A 0 241383 2.45 A 1249167 D Common Stock 125969 I See Footnote Common Stock 579000 I See Footnote Stock Option 2.45 2023-01-05 4 A 0 2400000 0.00 A 2033-01-05 Common Stock 2400000 2400000 D Reflects the executive's 2022 performance bonus award paid in Agenus Stock. The stock issued is fully-vested on the date of issuance but is subject to a lockup restriction with 50% of the award released on March 24, 2023 and 50% of the award released on June 24, 2023. $2.45 was the fair market value of Agenus Common Stock on January 5, 2023, the stock issuance date. Shares are held in Dr. Armen's IRA accounts. Dr. Armen is trustee and has investment authority for the Garo Armen 2020 2 Year AG GRAT holder of 479,000 shares of our Common Stock. Dr. Armen is a general partner in Pixie Partners, a General Partnership ("Pixie"), which as of the date of this report owns 100,000 shares of our Common Stock. Dr. Armen has a pecuniary interest in only a portion of the shares held by Pixie and disclaims beneficial ownership to the extent of his pecuniary interest therein. Option was granted on January 5, 2023 and awarded in accordance with the 2019 Plan. Option vests over a three-year period, with one-third of the options vesting on the one-year anniversary of the grant date, with the remainder vesting in equal quarterly installments thereafter. /s/ Christine Klaskin, as attorney-in-fact for Garo H. Armen 2023-01-09