X0306 4 2020-12-22 0 0000093314 VOLITIONRX LTD VNRX 0001651671 Micallef Jacob Vincent 13215 BEE CAVE PARKWAY SUITE 125 GALLERIA OAKS B AUSTIN TX 78738 0 1 0 0 Chief Scientific Officer Stock Option (Right to Buy) 4 2020-12-22 5 G 0 E 125000 0 D 2017-04-15 2022-04-15 Common Stock 125000 0 I Borlaug Limited Stock Option (Right to Buy) 4 2020-12-22 5 G 0 E 125000 0 A 2017-04-15 2022-04-15 Common Stock 125000 125000 D The option to purchase an aggregate of 125,000 shares of Common Stock of VolitionRx Limited (the "Issuer"), was granted to Dr. Micallef on April 15, 2016 under the Issuer's 2015 Stock Incentive Plan and transferred to Borlaug Limited ("Borlaug"), a consulting firm, on April 20, 2016. Dr. Micallef is a controlling director of Borlaug and has voting and dispositive control over the Common Stock issuable to Borlaug upon the exercise of the option. The option was then transferred by Borlaug to Dr. Micallef on December 22, 2020. /s/ Jacob Vincent Micallef 2020-12-23