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   &lt;div align="left" style="font-size: 10pt; margin-top: 12pt"&gt;&lt;b&gt;5.&lt;/b&gt;&amp;#160;&amp;#160;&lt;b&gt;Special Charges and Credits&lt;/b&gt;
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   &lt;div align="left" style="font-size: 10pt; margin-top: 6pt;  text-indent: 4%"&gt;Special charges and credits in the three and six months ended June&amp;#160;30, 2010 primarily related
   to settlement of certain legal disputes and related legal fees.
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   &lt;div align="left" style="font-size: 10pt; margin-top: 6pt;  text-indent: 4%"&gt;Special charges and credits in the three and six months ended June&amp;#160;30, 2009 primarily consist
   of an initial license fee related to an exclusive license agreement that grants us an exclusive
   license to develop and commercialize
   Opana&lt;sup style="font-size: 85%; vertical-align: text-top"&gt;&amp;#174;&lt;/sup&gt; and Opana&lt;sup style="font-size: 85%; vertical-align: text-top"&gt;&amp;#174;&lt;/sup&gt; ER in Canada, Australia and New Zealand (the &amp;#8220;Opana Territory&amp;#8221;). Regulatory
   approval must be received prior to any sale of the licensed products.
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   &lt;div style="margin-top: 18pt; font-size: 1pt"&gt;&amp;#160;
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