SECURITIES AND EXCHANGE COMMISSION
Washington, DC 20549

FORM 8-K

Current Report

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of report (Date of earliest event reported): May 10, 2004

MICROTEK MEDICAL HOLDINGS, INC.
(Exact Name of Registrant as Specified in Its Charter)

Georgia
(State or Other Jurisdiction of Incorporation)

0-24866	58-1746149
(Commission File Number)	(I.R.S. Employer Identification No.)
512 Lehmberg Road; Columbus, Mississippi	39702
(Address of Principal Executive Offices	(Zip Code)

(662) 327-1863
(Registrant’s Telephone Number, Including Area Code)

Item 12.   Results of Operations and Financial Conditions

On May 10, 2004, Microtek Medical Holdings, Inc. (the “Company”) issued a press release reporting its operating results for the quarter ended March 31, 2004. This press release is attached as Exhibit 99.1 to this report and is incorporated herein by reference.

The information in this Current Report on Form 8-K, including Exhibit 99.1, shall not be deemed “filed” for the purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liability of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, except as shall be expressly set forth by specific reference in such a filing.

Exhibits:

99.1 Press release dated May 10, 2004, announcing the Company's operating results for the quarter ended March 31, 2004

SIGNATURES

        Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has caused this report to be duly signed on its behalf by the undersigned hereunto duly authorized.

MICROTEK MEDICAL HOLDINGS, INC.

By: Dan R. Lee

Dan R. Lee, Chairman, President and Chief Executive
Officer

By: Roger G. Wilson

Roger G. Wilson, Chief Financial Officer

Dated:   May 10, 2004