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Income taxes - Reconciliation of federal tax rate to the effective rate (Details)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Income taxes    
U.S. statutory federal rate 21.00% 21.00%
State taxes, net of federal effect 8.88% 2.72%
Nontaxable foreign income (25.57%) (43.36%)
Research & Development Tax Credit (1.92%) (7.39%)
Permanent items (0.70%) (6.26%)
Goodwill impairment   20.31%
Valuation allowance for deferred tax assets 2.38% 0.65%
Total U.S. statutory federal tax rate to the effective rate 4.07% (12.33%)