X0306 4 2013-12-19 0 0000926617 VERMILLION, INC. VRML 0000926475 FEINBERG LARRY N C/O ORACLE INVESTMENT MANAGEMENT, INC. 200 GREENWICH AVENUE GREENWICH CT 06830 0 0 1 1 See Remarks 0000941901 ORACLE PARTNERS LP C/O ORACLE INVESTMENT MANAGEMENT, INC. 200 GREENWICH AVENUE GREENWICH CT 06830 0 0 1 1 See Remarks 0001577258 Oracle Ten Fund Master, LP 200 GREENWICH AVENUE GREENWICH CT 06830 0 0 1 1 See Remarks 0001317217 Oracle Associates LLC C/O ORACLE INVESTMENT MANAGEMENT, INC. 200 GREENWICH AVENUE GREENWICH CT 06830 0 0 1 1 See Remarks 0001012622 ORACLE INVESTMENT MANAGEMENT INC 200 GREENWICH AVENUE GREENWICH CT 06830 0 0 1 1 See Remarks Common Stock, par value $0.001 per share 2013-12-19 4 C 0 4339980 A 7139960 I See footnote Warrants to acquire Common Stock 2013-12-19 4 C 0 4339980 D 2013-08-11 2016-05-13 Common Stock 4339980 0 I See footnote See Exhibit 99.1, Note 1. See Exhibit 99.1, Note 2. See Exhibit 99.1, Note 3. Exhibit List: Exhibit 99.1 - Explanation of Responses Exhibit 99.2 - Joint Filer Information and Signatures Solely for purposes of Section 16 of the Exchange Act, each of the Oracle Funds (as defined in Exhibit 99.1), and Oracle Associates, LLC, Oracle Investment Management, Inc. and Mr. Feinberg, by virtue of their control over the Oracle Funds, may be deemed to be directors-by-deputization by virtue of the Oracle Funds' contractual right to designate a member of the board of directors of Vermillion, Inc. Eric Varma, a Senior Analyst of Oracle Investment Management, Inc., is a member of Vermillion, Inc.'s board of directors. /s/ Larry N. Feinberg 2013-12-23