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Note 8 - Share-based Compensation (Tables)
3 Months Ended
Mar. 31, 2024
Notes Tables  
Schedule of Share-based Compensation, Expense [Table Text Block]
   

Three months ended

 
   

March 31,

 
   

2024

   

2023

 

Research and development

  $ 115     $ 139  

Selling, general and administrative

    89       139  

Total share-based compensation

  $ 204     $ 278  
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
   

Number of

shares

   

Weighted

average

exercise

price

   

Weighted

average

remaining

contractual

term (years)

   

Aggregate

intrinsic value

(in thousands)

 
                                 

Balance, December 31, 2023

    2,486,767     $ 3.51       6.8     $ 43  

Stock options forfeited

    (47,657 )     2.26                  

Balance, March 31, 2024

    2,439,110     $ 3.54       6.6     $ 1  

Exercisable, March 31, 2024

    1,601,718     $ 4.49       5.6     $