Consolidated Statements of Operations - USD ($)	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015
Revenue:
Net product revenue	$ 517,000	$ 860,000
Collaboration agreement revenue	59,000	44,000
Total revenue	576,000	904,000
Costs and expenses:
Cost of goods sold	746,000	1,061,000
Research and development	3,330,000	1,518,000
Selling, general and administrative	4,108,000	3,734,000
Total costs and expenses	8,184,000	6,313,000
Operating loss	(7,608,000)	(5,409,000)
Other income (expense):
Interest expense, net	(1,736,000)	(1,386,000)
Write-off of deferred offering costs		(1,634,000)
Change in fair value of convertible preferred stock warrant liability	250,000	274,000
Change in fair value of maturity date preferred stock warrant liability	10,000	87,000
Change in fair value of convertible shareholder notes derivative liability	(1,224,000)	1,373,000
Other expense	(2,000)	(2,000)
Total other expense, net	(2,702,000)	(1,288,000)
Net loss	$ (10,310,000)	$ (6,697,000)
Net loss per share, basic and diluted (in dollars per share)	$ (0.10)	$ (0.36)
Weighted-average shares used in computing net loss per share, basic and diluted (in shares)	100,419,402	18,723,511