The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8

COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Aldeyra Therapeutics, Inc. COM 01438T106 3,456 594,834 SH   DFND 1 0 594,834 0
Arrowhead Pharmaceuticals, Inc. COM 04280A100 206,837 3,260,869 SH   DFND 1 0 3,260,869 0
BiomX Inc. COM 09090D103 20,662 2,133,402 SH   DFND 1 0 2,133,402 0
Castlight Health, Inc. CL B 14862Q100 1,079 811,295 SH   DFND 1 0 811,295 0
Catalyst Biosciences, Inc. COM NEW 14888D208 456 66,951 SH   DFND 1 0 66,951 0
Genocea Biosciences, Inc. COM NEW 372427401 298 143,964 SH   DFND 1 0 143,964 0
PhaseBio Pharmaceuticals, Inc. COM 717224109 9,819 1,607,044 SH   DFND 1 0 1,607,044 0
Protagonist Therapeutics, Inc. COM 74366E102 17,267 2,449,183 SH   DFND 1 0 2,449,183 0
Provention Bio, Inc. COM 74374N102 16,762 1,124,973 SH   DFND 1 0 1,124,973 0
Senseonics Holdings, Inc COM 81727U105 481 525,632 SH   DFND 1 0 525,632 0
Tracon Pharmaceuticals, Inc. COM NEW 89237H209 197 84,003 SH   DFND 1 0 84,003 0