Note 10 - Income Taxes (Details Textual) - USD ($)	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018
Deferred Tax Asset Based Upon Expected Income Tax Rates	$ 8,881,000
Valuation Allowance Percentage	100.00%
Operating Loss Carryforwards, Total	$ 18,335,000
Income Tax Expense (Benefit), Total	0	$ 0
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount	2,645,000	1,575,000
SEC Schedule, 12-09, Valuation Allowances and Reserves, Amount, Ending Balance		$ 768,000
State and Local Jurisdiction [Member] | Florida Department of Revenue [Member]
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount	$ (102,000)
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent	4.458%	5.50%
Orphan Drug Credit [Member]
Tax Credit Carryforward, Amount	$ 4,292,000